Algorithmic fairness in artificial intelligence for medicine and healthcare

RJ Chen, JJ Wang, DFK Williamson, TY Chen… - Nature biomedical …, 2023 - nature.com
In healthcare, the development and deployment of insufficiently fair systems of artificial
intelligence (AI) can undermine the delivery of equitable care. Assessments of AI models …

The coming decade in precision oncology: six riddles

A Wahida, L Buschhorn, S Fröhling, PJ Jost… - Nature Reviews …, 2023 - nature.com
High-throughput methods to investigate tumour omic landscapes have quickly catapulted
cancer specialists into the precision oncology era. The singular lesson of precision oncology …

Scaling vision transformers to gigapixel images via hierarchical self-supervised learning

RJ Chen, C Chen, Y Li, TY Chen… - Proceedings of the …, 2022 - openaccess.thecvf.com
Abstract Vision Transformers (ViTs) and their multi-scale and hierarchical variations have
been successful at capturing image representations but their use has been generally …

Demographic bias in misdiagnosis by computational pathology models

A Vaidya, RJ Chen, DFK Williamson, AH Song… - Nature Medicine, 2024 - nature.com
Despite increasing numbers of regulatory approvals, deep learning-based computational
pathology systems often overlook the impact of demographic factors on performance …

Priorities for cancer research in low-and middle-income countries: a global perspective

CS Pramesh, RA Badwe, N Bhoo-Pathy, CM Booth… - Nature medicine, 2022 - nature.com
Cancer research currently is heavily skewed toward high-income countries (HICs), with little
research conducted in, and relevant to, the problems of low-and middle-income countries …

Somatic genomic testing in patients with metastatic or advanced cancer: ASCO provisional clinical opinion

D Chakravarty, A Johnson, J Sklar… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE An ASCO provisional clinical opinion offers timely clinical direction to ASCO's
membership following publication or presentation of potentially practice-changing data from …

Cancer health disparities in racial/ethnic minorities in the United States

VA Zavala, PM Bracci, JM Carethers… - British journal of …, 2021 - nature.com
There are well-established disparities in cancer incidence and outcomes by race/ethnicity
that result from the interplay between structural, socioeconomic, socio-environmental …

Epidemiology and genomics of prostate cancer in Asian men

Y Zhu, M Mo, Y Wei, J Wu, J Pan, SJ Freedland… - Nature Reviews …, 2021 - nature.com
Prostate cancer is a global health problem, but incidence varies considerably across
different continents. Asia is traditionally considered a low-incidence area, but the incidence …

Artificial intelligence in oncology: current landscape, challenges, and future directions

W Lotter, MJ Hassett, N Schultz, KL Kehl… - Cancer …, 2024 - aacrjournals.org
Artificial intelligence (AI) in oncology is advancing beyond algorithm development to
integration into clinical practice. This review describes the current state of the field, with a …

Cancer gene mutation frequencies for the US population

G Mendiratta, E Ke, M Aziz, D Liarakos, M Tong… - Nature …, 2021 - nature.com
Mutations play a fundamental role in the development of cancer, and many create targetable
vulnerabilities. There are both public health and basic science benefits from the …