The microbiome–gut–brain axis in Parkinson disease—from basic research to the clinic
Evidence for a close bidirectional link between the brain and the gut has led to a paradigm
shift in neurology, especially in the case of Parkinson disease (PD), in which gastrointestinal …
shift in neurology, especially in the case of Parkinson disease (PD), in which gastrointestinal …
[HTML][HTML] Role and mechanism of gut microbiota in human disease
Y Chen, J Zhou, L Wang - Frontiers in cellular and infection …, 2021 - frontiersin.org
The human gut microbiome is a huge microbial community that plays an irreplaceable role
in human life. With the further development of research, the influence of intestinal flora on …
in human life. With the further development of research, the influence of intestinal flora on …
Fecal microbiota transplantation protects rotenone-induced Parkinson's disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 …
Z Zhao, J Ning, X Bao, M Shang, J Ma, G Li, D Zhang - Microbiome, 2021 - Springer
Background Parkinson's disease (PD) is a prevalent neurodegenerative disorder, displaying
not only well-known motor deficits but also gastrointestinal dysfunctions. Consistently, it has …
not only well-known motor deficits but also gastrointestinal dysfunctions. Consistently, it has …
Meta-analysis of the Parkinson's disease gut microbiome suggests alterations linked to intestinal inflammation
The gut microbiota is emerging as an important modulator of neurodegenerative diseases,
and accumulating evidence has linked gut microbes to Parkinson's disease (PD) …
and accumulating evidence has linked gut microbes to Parkinson's disease (PD) …
The microbiota-gut-brain axis in sleep disorders
Z Wang, Z Wang, T Lu, W Chen, W Yan, K Yuan… - Sleep medicine …, 2022 - Elsevier
Sleep is a complex physiological process and is a critical determinant of physical and
mental health. In the past decades, significant progress has been made in understanding …
mental health. In the past decades, significant progress has been made in understanding …
Prodromal Parkinson disease subtypes—key to understanding heterogeneity
In Parkinson disease (PD), pathological processes and neurodegeneration begin long
before the cardinal motor symptoms develop and enable clinical diagnosis. In this prodromal …
before the cardinal motor symptoms develop and enable clinical diagnosis. In this prodromal …
The gut microbiome in neurological disorders
Research into the role of the gut microbiome in modulating brain function has rapidly
increased over the past 10 years, albeit chiefly in animal models. Increasing clinical and …
increased over the past 10 years, albeit chiefly in animal models. Increasing clinical and …
The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives
The microbiota-gut-brain axis has been suggested to play an important role in Parkinson's
disease (PD). Here we performed a cross-sectional study to profile gut microbiota across …
disease (PD). Here we performed a cross-sectional study to profile gut microbiota across …
Biomarkers of conversion to α-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder
Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly
regarded as being in the early stages of a progressive neurodegenerative disease involving …
regarded as being in the early stages of a progressive neurodegenerative disease involving …