Leydig cells: formation, function, and regulation
BR Zirkin, V Papadopoulos - Biology of reproduction, 2018 - academic.oup.com
Herein we summarize important discoveries made over many years about Leydig cell
function and regulation. Fetal Leydig cells produce the high levels of androgen (testosterone …
function and regulation. Fetal Leydig cells produce the high levels of androgen (testosterone …
[HTML][HTML] Vimentin on the move: new developments in cell migration
The vimentin gene (VIM) encodes one of the 71 human intermediate filament (IF) proteins,
which are the building blocks of highly ordered, dynamic, and cell type-specific fiber …
which are the building blocks of highly ordered, dynamic, and cell type-specific fiber …
The potential role of miRNAs in the pathogenesis of adrenocortical carcinoma-A focus on signaling pathways interplay
Adrenocortical carcinoma (ACC) is a highly malignant infrequent tumor with a dismal
prognosis. microRNAs (miRNAs, miRs) are crucial in post-transcriptional gene expression …
prognosis. microRNAs (miRNAs, miRs) are crucial in post-transcriptional gene expression …
Intermediate filaments play a pivotal role in regulating cell architecture and function
J Lowery, ER Kuczmarski, H Herrmann… - Journal of Biological …, 2015 - ASBMB
Intermediate filaments (IFs) are composed of one or more members of a large family of
cytoskeletal proteins, whose expression is cell-and tissue type-specific. Their importance in …
cytoskeletal proteins, whose expression is cell-and tissue type-specific. Their importance in …
Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis
Summary T helper 2 (Th2) cells regulate helminth infections, allergic disorders, tumor
immunity, and pregnancy by secreting various cytokines. It is likely that there are …
immunity, and pregnancy by secreting various cytokines. It is likely that there are …
Lipid droplets and steroidogenic cells
Lipid droplets (LDs) in steroidogenic tissues have a cholesteryl ester (CE) core surrounded
by a phospholipid monolayer that is coated with associated proteins. Compared with other …
by a phospholipid monolayer that is coated with associated proteins. Compared with other …
Roles of vimentin in health and disease
More than 27 yr ago, the vimentin knockout (Vim−/−) mouse was reported to develop and
reproduce without an obvious phenotype, implying that this major cytoskeletal protein was …
reproduce without an obvious phenotype, implying that this major cytoskeletal protein was …
Mechanistic insight into toxicity of phthalates, the involved receptors, and the role of Nrf2, NF-κB, and PI3K/AKT signaling pathways
H Mohammadi, S Ashari - Environmental Science and Pollution Research, 2021 - Springer
The wide use of phthalates, as phthalates are used in the manufacturing of not only plastics
but also many others goods, has become a main concern in the current century because of …
but also many others goods, has become a main concern in the current century because of …
Granulosa cell‐layer stiffening prevents escape of mural granulosa cells from the post‐ovulatory follicle
X Wang, J Liao, H Shi, Y Zhao, W Ke, H Wu… - Advanced …, 2024 - Wiley Online Library
Ovulation is vital for successful reproduction. Following ovulation, cumulus cells and oocyte
are released, while mural granulosa cells (mGCs) remain sequestered within the post …
are released, while mural granulosa cells (mGCs) remain sequestered within the post …
Differential long non-coding RNA expression profiles in human oocytes and cumulus cells
J Bouckenheimer, P Fauque, CH Lecellier, C Bruno… - Scientific reports, 2018 - nature.com
Progress in assisted reproductive technologies strongly relies on understanding the
regulation of the dialogue between oocyte and cumulus cells (CCs). Little is known about …
regulation of the dialogue between oocyte and cumulus cells (CCs). Little is known about …