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The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation
Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …
[HTML][HTML] Papillomaviruses and endocytic trafficking
A Siddiqa, J Broniarczyk, L Banks - International journal of molecular …, 2018 - mdpi.com
Endocytic trafficking plays a major role in transport of incoming human papillomavirus
(HPVs) from plasma membrane to the trans Golgi network (TGN) and ultimately into the …
(HPVs) from plasma membrane to the trans Golgi network (TGN) and ultimately into the …
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
Subcortical brain structures are involved in developmental, psychiatric and neurological
disorders. Here we performed genome-wide association studies meta-analyses of …
disorders. Here we performed genome-wide association studies meta-analyses of …
STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle
Human papillomaviruses (HPV) activate a number of host factors to control their
differentiation-dependent life cycles. The transcription factor signal transducer and activator …
differentiation-dependent life cycles. The transcription factor signal transducer and activator …
Chromosome-level clam genome helps elucidate the molecular basis of adaptation to a buried lifestyle
Bivalve mollusks are economically important invertebrates that exhibit marked diversity in
benthic lifestyle and provide valuable resources for understanding the molecular basis of …
benthic lifestyle and provide valuable resources for understanding the molecular basis of …
Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling …
Deregulation of proliferation and differentiation-dependent signalling pathways is a hallmark
of human papillomavirus (HPV) infection. Although the manipulation of these pathways by …
of human papillomavirus (HPV) infection. Although the manipulation of these pathways by …
Cancer immunoinformatics: A promising era in the development of peptide vaccines for human papillomavirus-induced cervical cancer
Cancer immunoinformatics have led to new directions towards vaccine design from
predicted potential epitope candidates, which are able to stimulate the correct cellular or …
predicted potential epitope candidates, which are able to stimulate the correct cellular or …
The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-κB by merkel polyomavirus small tumour antigen
H Abdul-Sada, M Müller, R Mehta, R Toth… - …, 2017 - pmc.ncbi.nlm.nih.gov
Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with a high metastatic
potential. The majority of MCC cases are caused by the Merkel cell polyomavirus (MCPyV) …
potential. The majority of MCC cases are caused by the Merkel cell polyomavirus (MCPyV) …
Characteristics and functions of the Yip1 domain family (YIPF), multi-span transmembrane proteins mainly localized to the Golgi apparatus
S Shaik, H Pandey, SK Thirumalasetti… - Frontiers in cell and …, 2019 - frontiersin.org
Yip1 domain family (YIPF) proteins are multi-span, transmembrane proteins mainly localized
in the Golgi apparatus. YIPF proteins have been found in virtually all eukaryotes, suggesting …
in the Golgi apparatus. YIPF proteins have been found in virtually all eukaryotes, suggesting …
[HTML][HTML] Alkyl-imino sugars inhibit the pro-oncogenic ion channel function of human papillomavirus (HPV) E5
LF Wetherill, CW Wasson, G Swinscoe, D Kealy… - Antiviral research, 2018 - Elsevier
Despite the availability of prophylactic vaccines the burden of human papillomavirus (HPV)
associated malignancy remains high and there is a need to develop additional therapeutic …
associated malignancy remains high and there is a need to develop additional therapeutic …