The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation

JA Scarth, MR Patterson… - Journal of General …, 2021 - microbiologyresearch.org
Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …

[HTML][HTML] Papillomaviruses and endocytic trafficking

A Siddiqa, J Broniarczyk, L Banks - International journal of molecular …, 2018 - mdpi.com
Endocytic trafficking plays a major role in transport of incoming human papillomavirus
(HPVs) from plasma membrane to the trans Golgi network (TGN) and ultimately into the …

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

LM García-Marín, AI Campos, S Diaz-Torres… - Nature …, 2024 - nature.com
Subcortical brain structures are involved in developmental, psychiatric and neurological
disorders. Here we performed genome-wide association studies meta-analyses of …

STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle

EL Morgan, CW Wasson, L Hanson, D Kealy… - PLoS …, 2018 - journals.plos.org
Human papillomaviruses (HPV) activate a number of host factors to control their
differentiation-dependent life cycles. The transcription factor signal transducer and activator …

Chromosome-level clam genome helps elucidate the molecular basis of adaptation to a buried lifestyle

M Wei, H Ge, C Shao, X Yan, H Nie, H Duan, X Liao… - IScience, 2020 - cell.com
Bivalve mollusks are economically important invertebrates that exhibit marked diversity in
benthic lifestyle and provide valuable resources for understanding the molecular basis of …

Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling …

CW Wasson, EL Morgan, M Müller, RL Ross… - …, 2017 - pmc.ncbi.nlm.nih.gov
Deregulation of proliferation and differentiation-dependent signalling pathways is a hallmark
of human papillomavirus (HPV) infection. Although the manipulation of these pathways by …

Cancer immunoinformatics: A promising era in the development of peptide vaccines for human papillomavirus-induced cervical cancer

S Kaliamurthi, G Selvaraj, M Junaid… - Current …, 2018 - benthamdirect.com
Cancer immunoinformatics have led to new directions towards vaccine design from
predicted potential epitope candidates, which are able to stimulate the correct cellular or …

The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-κB by merkel polyomavirus small tumour antigen

H Abdul-Sada, M Müller, R Mehta, R Toth… - …, 2017 - pmc.ncbi.nlm.nih.gov
Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with a high metastatic
potential. The majority of MCC cases are caused by the Merkel cell polyomavirus (MCPyV) …

Characteristics and functions of the Yip1 domain family (YIPF), multi-span transmembrane proteins mainly localized to the Golgi apparatus

S Shaik, H Pandey, SK Thirumalasetti… - Frontiers in cell and …, 2019 - frontiersin.org
Yip1 domain family (YIPF) proteins are multi-span, transmembrane proteins mainly localized
in the Golgi apparatus. YIPF proteins have been found in virtually all eukaryotes, suggesting …

[HTML][HTML] Alkyl-imino sugars inhibit the pro-oncogenic ion channel function of human papillomavirus (HPV) E5

LF Wetherill, CW Wasson, G Swinscoe, D Kealy… - Antiviral research, 2018 - Elsevier
Despite the availability of prophylactic vaccines the burden of human papillomavirus (HPV)
associated malignancy remains high and there is a need to develop additional therapeutic …