Rationale Pathological gambling (PG) has recently been considered as a “behavioral” or
nonsubstance addiction. A comparison of the characteristics of PG and substance use …

This review summarizes evidence of dysregulated reward circuitry function in a range of
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …

Psychiatry is enormously complex. One of its main difficulties is to articulate the relationship
between the wide assortment of factors that may cause or contribute to psychiatric disorders …

Abstract Background The US National Institutes of Mental Health Research Domain Criteria
(RDoC) seek to stimulate research into biologically validated neuropsychological …

Substance dependence is characterized by compulsive drug-taking despite negative
consequences. Animal research suggests an underlying imbalance between goal-directed …

Importance Converging evidence has long identified both impulsivity and compulsivity as
key psychological constructs in drug addiction. Although dysregulated striatal-cortical …

In light of the upcoming eleventh edition of the International Classification of Diseases (ICD‐
11), the question arises as to the most appropriate classification of 'Pathological …

Serotonin reuptake inhibitor (SRI) medications are well established as first-line
pharmacotherapeutic treatment for Obsessive-Compulsive Disorder (OCD). However …

Objectives The current guidelines aim to evaluate the role of pharmacological agents in the
treatment of patients with compulsive sexual behaviour disorder (CSBD). They are intended …

This paper systematically reviews novel interventions developed and tested in healthy
controls that may be able to change the over or under controlled eating behaviours in eating …