Quinoline and quinolone dimers and their biological activities: An overview

XM Chu, C Wang, W Liu, LL Liang, KK Gong… - European journal of …, 2019 - Elsevier
Quinoline and quinolone motifs which act as structural subunits of more complex natural
products are ubiquitous in nature, and they are useful pharmacophores which play a pivotal …

A review exploring biological activities of hydrazones

G Verma, A Marella, M Shaquiquzzaman… - Journal of Pharmacy …, 2014 - journals.lww.com
The development of novel compounds, hydrazones has shown that they possess a wide
variety of biological activities viz. antimicrobial, anticonvulsant, antidepressant, anti …

Antituberculosis drug research: a critical overview

Beena, DS Rawat - Medicinal research reviews, 2013 - Wiley Online Library
The increasing drug resistance of M ycobacterium tuberculosis to the currently used drugs
and HIV coinfection has caused alarm in the international scientific community …

Synthesis, characterization, in silico DFT, molecular docking, and dynamics simulation studies of phenylhydrazono phenoxyquinolones for their hypoglycemic efficacy

N Lohitha, PH Kumar, S Sarveswari, S Rathod… - ACS …, 2024 - ACS Publications
A series of novel 24 phenylhydrazono phenoxyquinoline derivatives were synthesized with
moderate to excellent yield and screened for their efficacy against the α-amylase enzyme …

Diversity oriented design of various hydrazides and their in vitro evaluation against Mycobacterium tuberculosis H37Rv strains

A Manvar, A Bavishi, A Radadiya, J Patel… - Bioorganic & medicinal …, 2011 - Elsevier
Control and prevention of tuberculosis is a major challenge, as one-third of the world's
population is infected with Mycobacterium tuberculosis. The resurgence of tuberculosis and …

[HTML][HTML] The multiple faces of eugenol. A versatile starting material and building block for organic and bio-organic synthesis and a convenient precursor toward bio …

TS Kaufman - Journal of the Brazilian Chemical Society, 2015 - SciELO Brasil
Phenylpropenes are produced by plants as part of their defense strategy against
microorganisms and animals, and also as floral attractants of pollinators. Eugenol, the main …

Synthesis, characterization and biological activity of ferrocene-based Schiff base ligands and their metal (II) complexes

YT Liu, GD Lian, DW Yin, BJ Su - … Acta Part A: Molecular and Biomolecular …, 2013 - Elsevier
Metal (II) complexes derived from S-benzyl-N-(1-ferrocenyl-3-(4-methylbenzene)
acrylketone) dithiocarbazate; HL1, S-benzyl-N-(1-ferrocenyl-3-(4-chlorobenzene) …

Quinoline and quinolones: promising scaffolds for future antimycobacterial agents

S Singh, G Kaur, V Mangla… - Journal of enzyme …, 2015 - Taylor & Francis
Tuberculosis (TB) is still a major health concern worldwide. The increasing incidences of
multi-drug-resistant tuberculosis (MDR-TB) necessitate the development of new anti-TB …

Synthesis and in vitro antitubercular activity of ferrocene-based hydrazones

A Mahajan, L Kremer, S Louw, Y Guéradel… - Bioorganic & medicinal …, 2011 - Elsevier
We report here the synthesis and in vitro antitubercular activity of a new series of ferrocenyl
derivatives. The quinoline-ferrocene hybrid 5 exhibited significant activity (MIC= 2.5–5 …

[HTML][HTML] Design, synthesis and antimycobacterial activity of thiazolidine-2, 4-dione-based thiosemicarbazone derivatives

N Trotsko, J Golus, P Kazimierczak, A Paneth… - Bioorganic …, 2020 - Elsevier
The two series of thiosemicarbazone derivatives with thiazolidine-2, 4-dione (TZD) core
were designed and synthesized. The antimycobacterial activity of the target compounds was …