Transcriptional regulatory network of high-value active ingredients in medicinal plants

H Zheng, X Fu, J Shao, Y Tang, M Yu, L Li… - Trends in Plant …, 2023 - cell.com
High-value active ingredients in medicinal plants have attracted research attention because
of their benefits for human health, such as the antimalarial artemisinin, anticardiovascular …

Multilayered regulation of secondary metabolism in medicinal plants

Y Zhao, G Liu, F Yang, Y Liang, Q Gao, C **ang… - Molecular …, 2023 - Springer
Medicinal plants represent a huge reservoir of secondary metabolites (SMs), substances
with significant pharmaceutical and industrial potential. However, obtaining secondary …

Role of bZIP transcription factors in the regulation of plant secondary metabolism

H Han, C Wang, X Yang, L Wang, J Ye, F Xu, Y Liao… - Planta, 2023 - Springer
Main conclusion This study provides an overview of the structure, classification, regulatory
mechanisms, and biological functions of the basic (region) leucine zipper transcription …

Transcriptional regulation of secondary metabolite biosynthesis in plants

B Patra, C Schluttenhofer, Y Wu, S Pattanaik… - Biochimica et Biophysica …, 2013 - Elsevier
Plants produce thousands of secondary metabolites (aka specialized metabolites) of diverse
chemical nature. These compounds play important roles in protecting plants under adverse …

Alkaloid biosynthesis: metabolism and trafficking

J Ziegler, PJ Facchini - Annu. Rev. Plant Biol., 2008 - annualreviews.org
Alkaloids represent a highly diverse group of compounds that are related only by the
occurrence of a nitrogen atom in a heterocyclic ring. Plants are estimated to produce …

The Transcription Factor CrWRKY1 Positively Regulates the Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus

N Suttipanta, S Pattanaik, M Kulshrestha… - Plant …, 2011 - academic.oup.com
Catharanthus roseus produces a large array of terpenoid indole alkaloids (TIAs) that are an
important source of natural or semisynthetic anticancer drugs. The biosynthesis of TIAs is …

A differentially regulated AP 2/ERF transcription factor gene cluster acts downstream of a MAP kinase cascade to modulate terpenoid indole alkaloid biosynthesis in …

P Paul, SK Singh, B Patra, X Sui, S Pattanaik… - New …, 2017 - Wiley Online Library
Catharanthus roseus produces bioactive terpenoid indole alkaloids (TIA s), including the
chemotherapeutics, vincristine and vinblastine. Transcriptional regulation of TIA …

Jasmonates and related oxylipins in plant responses to pathogenesis and herbivory

EE Farmer, E Alméras, V Krishnamurthy - Current opinion in plant biology, 2003 - Elsevier
The vigorous production of oxygenated fatty acids (oxylipins) is a characteristic response to
pathogenesis and herbivory, and is often accompanied by the substantial release of small …

The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus

A Van Moerkercke, P Steensma, F Schweizer… - Proceedings of the …, 2015 - pnas.org
Plants make specialized bioactive metabolites to defend themselves against attackers. The
conserved control mechanisms are based on transcriptional activation of the respective …

Camptothecin, over four decades of surprising findings

A Lorence, CL Nessler - Phytochemistry, 2004 - Elsevier
Camptothecin (CPT) is a modified monoterpene indole alkaloid produced by Camptotheca
acuminata (Nyssaceae), Nothapodytes foetida, Pyrenacantha klaineana, Merrilliodendron …