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Hypervirulent Klebsiella pneumoniae
J Chen, H Zhang, X Liao - Infection and Drug Resistance, 2023 - Taylor & Francis
Hypervirulent Klebsiella pneumoniae (hvKP), especially multidrug-resistant hvKP (MDR-
hvKP) infections, are distributed globally, and lead to several outbreaks with high …
hvKP) infections, are distributed globally, and lead to several outbreaks with high …
Autophagy, cell death, and cytokines in K. pneumoniae infection: therapeutic perspectives
Klebsiella pneumoniae is a notorious nosocomial pathogen causing a wide range of
infections. The increasing trend of antimicrobial resistance obtained by the species …
infections. The increasing trend of antimicrobial resistance obtained by the species …
Capsule type defines the capability of Klebsiella pneumoniae in evading Kupffer cell capture in the liver
Polysaccharide capsule is the main virulence factor of K. pneumoniae, a major pathogen of
bloodstream infections in humans. While more than 80 capsular serotypes have been …
bloodstream infections in humans. While more than 80 capsular serotypes have been …
CircCDC42-encoded CDC42-165aa regulates macrophage pyroptosis in Klebsiella pneumoniae infection through Pyrin inflammasome activation
N Xu, J Jiang, F Jiang, G Dong, L Meng… - Nature …, 2024 - nature.com
The circular RNA (circRNA) family is a group of endogenous non-coding RNAs (ncRNAs)
that have critical functions in multiple physiological and pathological processes, including …
that have critical functions in multiple physiological and pathological processes, including …
Capsules and their traits shape phage susceptibility and plasmid conjugation efficiency
Bacterial evolution is affected by mobile genetic elements like phages and conjugative
plasmids, offering new adaptive traits while incurring fitness costs. Their infection is affected …
plasmids, offering new adaptive traits while incurring fitness costs. Their infection is affected …
Klebsiella pneumoniae causes bacteremia using factors that mediate tissue-specific fitness and resistance to oxidative stress
CL Holmes, AE Wilcox, V Forsyth, SN Smith… - PLoS …, 2023 - journals.plos.org
Gram-negative bacteremia is a major cause of global morbidity involving three phases of
pathogenesis: initial site infection, dissemination, and survival in the blood and filtering …
pathogenesis: initial site infection, dissemination, and survival in the blood and filtering …
[HTML][HTML] Presence of hypervirulence-associated determinants in Klebsiella pneumoniae from hospitalised patients in Germany
Background Klebsiella (K.) pneumoniae is a ubiquitous Gram-negative bacterium and a
common coloniser of animals and humans. Today, K. pneumoniae is one of the most …
common coloniser of animals and humans. Today, K. pneumoniae is one of the most …
Engineered exosomes as a prospective therapy for diabetic foot ulcers
L Guo, D **ao, H **ng, G Yang, X Yang - Burns & trauma, 2024 - academic.oup.com
Diabetic foot ulcer (DFU), characterized by high recurrence rate, amputations and mortality,
poses a significant challenge in diabetes management. The complex pathology involves …
poses a significant challenge in diabetes management. The complex pathology involves …
Resistance and virulence features of hypermucoviscous Klebsiella pneumoniae from bloodstream infections: Results of a nationwide Italian surveillance study
Among Enterobacterales, Klebsiella pneumoniae (Kp) is one of the major opportunistic
pathogens causing hospital-acquired infections. The most problematic phenomenon linked …
pathogens causing hospital-acquired infections. The most problematic phenomenon linked …
Adaptive evolution of carbapenem-resistant hypervirulent Klebsiella pneumoniae in the urinary tract of a single patient
S Song, S Yang, R Zheng, D Yin, Y Cao… - Proceedings of the …, 2024 - pnas.org
The emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) is
a growing concern due to its high mortality and limited treatment options. Although …
a growing concern due to its high mortality and limited treatment options. Although …