mACPpred 2.0: Stacked deep learning for anticancer peptide prediction with integrated spatial and probabilistic feature representations

VK Sangaraju, NT Pham, L Wei, X Yu… - Journal of Molecular …, 2024 - Elsevier
Anticancer peptides (ACPs), naturally occurring molecules with remarkable potential to
target and kill cancer cells. However, identifying ACPs based solely from their primary amino …

MST-m6A: A Novel Multi-Scale Transformer-based Framework for Accurate Prediction of m6A Modification Sites Across Diverse Cellular Contexts

Q Su, NT Pham, L Wei, B Manavalan - Journal of Molecular Biology, 2024 - Elsevier
Abstract N6-methyladenosine (m6A) modification, a prevalent epigenetic mark in eukaryotic
cells, is crucial in regulating gene expression and RNA metabolism. Accurately identifying …

DOGpred: A Novel Deep Learning Framework for Accurate Identification of Human O-linked Threonine Glycosylation Sites

KW Lee, NT Pham, HJ Min, HW Park, JW Lee… - Journal of Molecular …, 2025 - Elsevier
O-linked glycosylation is a crucial post-transcriptional modification that regulates protein
function and biological processes. Dysregulation of this process is associated with various …

Voting-ac4C: Pre-trained large RNA language model enhances RNA N4-acetylcytidine site prediction

Y Jia, Z Zhang, S Yan, Q Zhang, L Wei, F Cui - International Journal of …, 2024 - Elsevier
Abstract RNA N4-acetylcytidine (ac4C) modification plays a crucial role in gene expression
regulation. However, existing prediction methods face limitations in capturing RNA …

DPNN-ac4C: a dual-path neural network with self-attention mechanism for identification of N4-acetylcytidine (ac4C) in mRNA

J Yuan, Z Wang, Z Pan, A Li, Z Zhang, F Cui - Bioinformatics, 2024 - academic.oup.com
Motivation The modification of N4-acetylcytidine (ac4C) in RNA is a conserved epigenetic
mark that plays a crucial role in post-transcriptional regulation, mRNA stability, and …

Caps-ac4C: an effective computational framework for identifying N4-acetylcytidine sites in human mRNA based on deep learning

L Yao, P **e, D Dong, Y Guo, J Guan, W Zhang… - Journal of Molecular …, 2025 - Elsevier
Abstract N4-acetylcytidine (ac4C) is a crucial post-transcriptional modification in human
mRNA, involving the acetylation of the nitrogen atom at the fourth position of cytidine. This …

NBCR-ac4C: A Deep Learning Framework Based on Multivariate BERT for Human mRNA N4-Acetylcytidine Sites Prediction

W He, Y Han, Y Zuo, Y Bai, F Guo - Journal of Chemical …, 2024 - ACS Publications
N4-acetylcytidine (ac4C) plays a crucial role in regulating cellular biological processes,
particularly in gene expression regulation and disease development. However, experiments …

Deepstack-ACE: A deep stacking-based ensemble learning framework for the accelerated discovery of ACE inhibitory peptides

P Charoenkwan, P Chumnanpuen, N Schaduangrat… - Methods, 2025 - Elsevier
Identifying angiotensin-I-converting enzyme (ACE) inhibitory peptides accurately is crucial
for understanding the primary factor that regulates the renin-angiotensin system and for …

How well does the adaptive feature representation learning approach identify human mRNA N4-acetylcytidine sites?

R Kumar, Y Wang, SK Dhanda - Molecular Therapy-Nucleic Acids, 2024 - cell.com
RNA molecules undergo extensive modifications by enzymes known as RNA modification
enzymes. Over 170 different types of these post-transcriptional modifications have been …

Advances in RNA secondary structure prediction and RNA modifications: Methods, data, and applications

S Yang, NT Pham, Z Li, JY Baik, J Lee, T Zhai… - arxiv preprint arxiv …, 2025 - arxiv.org
Due to the hierarchical organization of RNA structures and their pivotal roles in fulfilling RNA
functions, the formation of RNA secondary structure critically influences many biological …