Context South Africa has the most HIV infections of any country in the world, yet little is
known about the adolescent continuum of care from HIV diagnosis through viral …

Background Almost 30% of children in Southern Africa are HIV exposed but uninfected
(HEU) and experience exposures that could increase vulnerability to infectious diseases …

The report covers the epidemiology of HIV from both social and biomedical points of view,
providing us not only with statistical data on HIV prevalence, HIV incidence and antiretroviral …

Background The poor health of South Africans is known to be associated with a quadruple
disease burden. In the second National Burden of Disease (NBD) study, we aimed to …

Summary Since the 2009 Lancet Health in South Africa Series, important changes have
occurred in the country, resulting in an increase in life expectancy to 60 years. Historical …

PROBLEM: The World Health Organization has produced clear guidelines for the prevention
of mother-to-child transmission (PMTCT) of the human immunodeficiency virus (HIV) …

Background The epidemiology of paediatric bloodstream infection (BSI) in Sub-Saharan
Africa is poorly documented with limited data on hospital-acquired sepsis, impact of HIV …

BACKGROUND: Increased morbidity and mortality from lower respiratory tract infection
(LRTI) has been suggested in HIV-exposed uninfected (HEU) children; however, the …

Executive summary Mathematical models have an important role to play in identifying which
interventions are having the greatest impact, and where HIV interventions are most needed …

This working paper provides a detailed technical description of the THEMBISA model, an
integrated demographic and epidemiological model of the South African HIV/AIDS epidemic …