Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

The increasing impact of cancer on worldwide mortality makes the research of novel
chemotherapeutic agents a current and challenging issue. In the recent years, transition …

Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …

Photodynamic therapy (PDT) is a noninvasive medical technique that has received
increasing attention over the last years and been applied for the treatment of certain types of …

Ruthenium complexes with bioactive ligands are becoming promising substitutes for
platinum complexes due to their precise action against various cancers. In the present study …

Photodynamic therapy (PDT) through the generation of singlet oxygen utilizing
photosensitizers (PSs) is significantly limited under hypoxic conditions in solid tumors. So it …

Despite their past triumphs, platinum-based therapeutics remain limited by chemo-
resistance and severe side effects. As an alternative therapeutic modality which bypasses …

Photodynamic therapy (PDT) is a noninvasive treatment for certain types of cancer, bacterial,
fungal and viral infections, and skin diseases. In recent years, adaptation of this treatment so …

An optimal cancer chemotherapy regimen should effectively address the drug resistance of
tumors while eliciting antitumor‐immune responses. Research has shown that non …

The relentless increase in drug resistance of platinum-based chemotherapeutics has
opened the scope for other new cancer therapies with novel mechanisms of action (MoA) …