Reperfusion is mandatory to salvage ischemic myocardium from infarction, but reperfusion
per se contributes to injury and ultimate infarct size. Therefore, cardioprotection beyond that …

Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …

Cardiovascular disease is the leading cause of death in western countries. Among
cardiovascular diseases, myocardial infarction represents a life-threatening condition …

Background A growing body of evidence suggests that stem cell-derived exosomal
microRNAs (miRNAs) could be a promising cardioprotective therapy in the context of …

Though experimental, stem cell transplantation has the potential to improve the condition of
the heart after myocardial infarction. It does so by reducing infarct size and inducing repair of …

Remote ischemic preconditioning (rIPC) induced by cycles of transient limb ischemia and
reperfusion is a powerful cardioprotective strategy with additional pleiotropic effects …

The heart is a very complex conglomeration of organized interactions between various
different cell types that all aid in facilitating myocardial function through contractility, sufficient …

Aims Differential microRNA expression in peripheral blood has been observed in patients
with heart failure, suggesting their value as potential biomarkers and likely contributors to …

Rationale: In some patients with type 2 diabetes mellitus (DM) without hypertension, cardiac
hypertrophy and attenuated cardiac function are observed, and this insult is termed diabetic …

Background MicroRNAs (miRNAs) are important post-transcriptional regulators that have
been demonstrated to play an important role in human diseases. Elucidating the …