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Review on strategies and technologies for exosome isolation and purification
J Chen, P Li, T Zhang, Z Xu, X Huang… - … in bioengineering and …, 2022 - frontiersin.org
Exosomes, a nano-sized subtype of extracellular vesicles secreted from almost all living
cells, are capable of transferring cell-specific constituents of the source cell to the recipient …
cells, are capable of transferring cell-specific constituents of the source cell to the recipient …
The updated role of exosomal proteins in the diagnosis, prognosis, and treatment of cancer
X Wang, J Huang, W Chen, G Li, Z Li… - Experimental & molecular …, 2022 - nature.com
Exosomes are vesicles encompassed by a lipid bilayer that are released by various living
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …
Aptamer-based detection of circulating targets for precision medicine
L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
Application of exosomes as liquid biopsy in clinical diagnosis
B Zhou, K Xu, X Zheng, T Chen, J Wang… - Signal transduction and …, 2020 - nature.com
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
Exosomal miRNA-mediated intercellular communications and immunomodulatory effects in tumor microenvironments
Extracellular communication, in other words, crosstalk between cells, has a pivotal role in
the survival of an organism. This communication occurs by different methods, one of which is …
the survival of an organism. This communication occurs by different methods, one of which is …
Potential clinical utility of liquid biopsies in ovarian cancer
Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …
of the main challenges in the management of OC is the late clinical presentation of disease …
Extracellular vesicles in cancer: cell-to-cell mediators of metastasis
Tumor-secreted extracellular vesicles (EVs) are critical mediators of intercellular
communication between tumor cells and stromal cells in local and distant …
communication between tumor cells and stromal cells in local and distant …
The biology and function of exosomes in cancer
R Kalluri - The Journal of clinical investigation, 2016 - jci.org
Humans circulate quadrillions of exosomes at all times. Exosomes are a class of
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Exosomes are lipid-bilayer-enclosed extracellular vesicles that contain proteins and nucleic
acids. They are secreted by all cells and circulate in the blood. Specific detection and …
acids. They are secreted by all cells and circulate in the blood. Specific detection and …
Extracellular vesicles: composition, biological relevance, and methods of study
The release of extracellular vesicles (EVs), including exosomes and microvesicles, is a
phenomenon shared by many cell types as a means of communicating with other cells and …
phenomenon shared by many cell types as a means of communicating with other cells and …