Therapeutically harnessing extracellular vesicles
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …
from the study of fundamental biology to a subject of significant clinical relevance. The …
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
The ability of exosomes to transfer cargo from donor to acceptor cells, thereby triggering
phenotypic changes in the latter, has generated substantial interest in the scientific …
phenotypic changes in the latter, has generated substantial interest in the scientific …
Extracellular vesicles: exosomes, microvesicles, and friends
G Raposo, W Stoorvogel - Journal of Cell Biology, 2013 - rupress.org
Cells release into the extracellular environment diverse types of membrane vesicles of
endosomal and plasma membrane origin called exosomes and microvesicles, respectively …
endosomal and plasma membrane origin called exosomes and microvesicles, respectively …
Extracellular vesicles: biology and emerging therapeutic opportunities
S El Andaloussi, I Mäger, XO Breakefield… - Nature reviews Drug …, 2013 - nature.com
Within the past decade, extracellular vesicles have emerged as important mediators of
intercellular communication, being involved in the transmission of biological signals …
intercellular communication, being involved in the transmission of biological signals …
Extracellular vesicles: unique intercellular delivery vehicles
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound carriers
with complex cargoes including proteins, lipids, and nucleic acids. While the release of EVs …
with complex cargoes including proteins, lipids, and nucleic acids. While the release of EVs …
[HTML][HTML] Exosome theranostics: biology and translational medicine
C He, S Zheng, Y Luo, B Wang - Theranostics, 2018 - ncbi.nlm.nih.gov
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules,
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …
Classification, functions, and clinical relevance of extracellular vesicles
Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into
their environment. Why do cells release vesicles? Initial studies showed that eukaryotic …
their environment. Why do cells release vesicles? Initial studies showed that eukaryotic …
Extracellular vesicles and neurodegenerative diseases
AF Hill - Journal of Neuroscience, 2019 - Soc Neuroscience
Extracellular vesicles (EVs) include exosomes and microvesicles and have been shown to
have roles in the CNS ranging from the removal of unwanted biomolecules to intercellular …
have roles in the CNS ranging from the removal of unwanted biomolecules to intercellular …
Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy
Y Lee, S El Andaloussi, MJA Wood - Human molecular genetics, 2012 - academic.oup.com
Exosomes and microvesicles are extracellular nanovesicles released by most but not all
cells. They are specifically equipped to mediate intercellular communication via the transfer …
cells. They are specifically equipped to mediate intercellular communication via the transfer …
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood
L Cheng, RA Sharples, BJ Scicluna… - Journal of extracellular …, 2014 - Taylor & Francis
Introduction microRNA (miRNA) are small non-coding RNA species that are transcriptionally
processed in the host cell and released extracellularly into the bloodstream. Normally …
processed in the host cell and released extracellularly into the bloodstream. Normally …