Properties and applications of PDMS for biomedical engineering: A review

I Miranda, A Souza, P Sousa, J Ribeiro… - Journal of functional …, 2021 - mdpi.com
Polydimethylsiloxane (PDMS) is an elastomer with excellent optical, electrical and
mechanical properties, which makes it well-suited for several engineering applications. Due …

Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023 - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Frontiers in the treatment of glioblastoma: Past, present and emerging

TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed… - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

Engineering poly (ethylene glycol) nanoparticles for accelerated blood clearance inhibition and targeted drug delivery

Y Tian, Z Gao, N Wang, M Hu, Y Ju, Q Li… - Journal of the …, 2022 - ACS Publications
Surface modification with poly (ethylene glycol)(PEGylation) is an effective strategy to
improve the colloidal stability of nanoparticles (NPs) and is often used to minimize cellular …

Principles of nanoparticle design for overcoming biological barriers to drug delivery

E Blanco, H Shen, M Ferrari - Nature biotechnology, 2015 - nature.com
Biological barriers to drug transport prevent successful accumulation of nanotherapeutics
specifically at diseased sites, limiting efficacious responses in disease processes ranging …

Role of nanoparticle mechanical properties in cancer drug delivery

Y Hui, X Yi, F Hou, D Wibowo, F Zhang, D Zhao… - ACS …, 2019 - ACS Publications
The physicochemical properties of nanoparticles play critical roles in regulating nano-bio
interactions. Whereas the effects of the size, shape, and surface charge of nanoparticles on …

Impact of particle elasticity on particle-based drug delivery systems

AC Anselmo, S Mitragotri - Advanced drug delivery reviews, 2017 - Elsevier
Modification of nano/micro-particle physical parameters (eg size, shape, surface charge) has
proven to be an effective method to enhance their delivery abilities. Recently, advances in …

Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake.

J Sun, L Zhang, J Wang, Q Feng, D Liu… - … (deerfield beach, fla.), 2014 - europepmc.org
Core-shell nanoparticles (NPs) with lipid shells and varying water content and rigidity but
with the same chemical composition, size, and surface properties are assembled using a …

Influence of nanomedicine mechanical properties on tumor targeting delivery

Z Li, C **ao, T Yong, Z Li, L Gan, X Yang - Chemical Society Reviews, 2020 - pubs.rsc.org
Modulating nanomedicine mechanical properties for enhanced drug delivery to tumors has
attracted increasing attention in the past few decades. In this tutorial review, we analyze the …

Hydrogel nanoarchitectonics: an evolving paradigm for ultrasensitive biosensing

ZS Nishat, T Hossain, MN Islam, HP Phan, MA Wahab… - Small, 2022 - Wiley Online Library
The integration of nanoarchitectonics and hydrogel into conventional biosensing platforms
offers the opportunities to design physically and chemically controlled and optimized soft …