The vaginal microbiome and the risk of preterm birth: a systematic review and network meta-analysis

U Gudnadottir, JW Debelius, J Du, LW Hugerth… - Scientific reports, 2022 - nature.com
Preterm birth is a major cause of neonatal morbidity and mortality worldwide. Increasing
evidence links the vaginal microbiome to the risk of spontaneous preterm labour that leads …

Roles of the microbiota of the female reproductive tract in gynecological and reproductive health

B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - journals.asm.org
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

Microbial diversity in the vaginal microbiota and its link to pregnancy outcomes

A Baud, KH Hillion, C Plainvert, V Tessier, A Tazi… - Scientific reports, 2023 - nature.com
The vaginal microbiota refers to the microorganisms that reside in the vagina. These
microorganisms contribute significantly to a woman's reproductive and general health. A …

Integrating compositional and functional content to describe vaginal microbiomes in health and disease

JB Holm, MT France, P Gajer, B Ma, RM Brotman… - Microbiome, 2023 - Springer
Background A Lactobacillus-dominated vaginal microbiome provides the first line of defense
against adverse genital tract health outcomes. However, there is limited understanding of …

The vaginal microbiota of pregnant women varies with gestational age, maternal age, and parity

R Romero, KR Theis, N Gomez-Lopez… - Microbiology …, 2023 - journals.asm.org
The composition of the vaginal microbiota is heavily influenced by pregnancy and may factor
into pregnancy complications, including spontaneous preterm birth. However, results among …

Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota

V Mercado-Evans, ME Mejia, JJ Zulk, S Ottinger… - Nature …, 2024 - nature.com
Abstract Group B Streptococcus (GBS) is a pervasive perinatal pathogen, yet factors driving
GBS dissemination in utero are poorly defined. Gestational diabetes mellitus (GDM), a …

Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and …

C Farr Zuend, A Lamont, L Noel-Romas, S Knodel… - Microbiome, 2023 - Springer
Background Cervicovaginal inflammation has been linked to negative reproductive health
outcomes including the acquisition of HIV, other sexually transmitted infections, and cervical …

Predicting preterm birth through vaginal microbiota, cervical length, and WBC using a machine learning model

S Park, J Moon, N Kang, YH Kim, YA You… - Frontiers in …, 2022 - frontiersin.org
An association between the vaginal microbiome and preterm birth has been reported.
However, in practice, it is difficult to predict premature birth using the microbiome because …

Joint effects of individual socioeconomic status and residential neighborhood context on vaginal microbiome composition

M Dixon, AL Dunlop, EJ Corwin… - Frontiers in Public …, 2023 - frontiersin.org
Introduction The vaginal microbiome is a dynamic ecosystem that is important for women's
health. Its composition has been associated with risk for menopausal symptoms, sexually …

The vaginal immunoproteome for the prediction of spontaneous preterm birth: A retrospective longitudinal study

Z Shaffer, R Romero, AL Tarca, J Galaz… - Elife, 2024 - elifesciences.org
Background: Preterm birth is the leading cause of neonatal morbidity and mortality
worldwide. Most cases of preterm birth occur spontaneously and result from preterm labor …