Antibiotics are recognized widely for their benefits when used appropriately. However, they
are often used inappropriately despite the importance of responsible use within good clinical …

Early initiation of a multimodal treatment strategy in the management of vasopressors during
septic shock has been advocated to reduce delays in restoring adequate organ perfusion …

We compared epidemiology of intra-abdominal infection (IAI) between immunocompromised
and non-immunocompromised ICU patients and identified risk factors for mortality. We …

Damage-control surgery (DCS) is a strategy adopted to limit initial operative interventions in
the unstable surgical patient, delaying definitive repairs and abdominal wall closure until …

Intra-abdominal candidiasis (IAC) is one of the most common of invasive candidiasis
observed in critically ill patients. It is associated with high mortality, with up to 50% of deaths …

This comprehensive review aims to provide a practical guide for intensivists, focusing on
enhancing patient care associated with nosocomial peritonitis (NP). It explores the …

Sepsis, a syndrome caused by a dysregulated host response to infection and characterized
by life-threatening organ dysfunction, particularly septic shock and sepsis-associated organ …

Sepsis is a leading cause of disability and mortality worldwide. The pathophysiology of
sepsis relies on the maladaptive host response to pathogens that fosters unbalanced organ …

Sepsis therapies including care bundles, fluid resuscitation, and source control procedures
may be better guided by validated phenotypes than universal application. Novel biomarkers …

Early diagnosis and prompt management are essential to enhance the outcomes of patients
with sepsis and septic shock. Over the past two decades, evidence-based guidelines have …