Coumarin-based fluorogenic probes have emerged as preferred imaging tools to real-time
and non-invasively monitor target analyte (s) in biological systems, due to their inherent …

Enzymes and their regulations are employed as indicators for various diseases, including
cancer. To directly analyze the activity of the enzymes within a biological system, enzyme …

Bioorthogonal pretargeting optical imaging shows the potential for enhanced diagnosis and
prognosis. However, the bioorthogonal handles, known for being “always reactive”, may …

β-Galactosidase (β-gal) is the gold standard marker of cellular senescence, which is linked
with various age-related diseases. Therefore, it is essential to develop more excellent …

Early diagnosis and therapy are clinically crucial in decreasing mortality from breast
carcinoma. However, the existing probes have difficulty in accurately identifying the margins …

Abstract Beta-galactosidase (β-gal), a typical glycosidase catalyzing the hydrolysis of
glycosidic bonds, is regarded as a vital biomarker for cell senescence and cancer …

In situ precise detection of bioactive molecules with high sensitivity and spatiotemporal
resolution is essential for studying physiological events and disease diagnosis. The …

Although the clearance of senescent cells has been proven to slow down the aging process
and promote anti‐cancer chemotherapy, the development of senolytics remains challenging …

Specific imaging of cellular senescence emerges as a promising strategy for early diagnosis
and treatment of various age-related diseases. The currently available imaging probes are …

Population aging has increased the global prevalence of aging‐related diseases, including
cancer, sarcopenia, neurological disease, arthritis, and heart disease. Understanding aging …