High-risk prostate cancer—classification and therapy

AJ Chang, KA Autio, M Roach III, HI Scher - Nature reviews Clinical …, 2014 - nature.com
Approximately 15% of patients with prostate cancer are diagnosed with high-risk disease.
However, the current definitions of high-risk prostate cancer include a heterogeneous group …

Salvage therapy for prostate cancer after radical prostatectomy

NG Zaorsky, J Calais, S Fanti, D Tilki, T Dorff… - Nature Reviews …, 2021 - nature.com
More than 40% of men with intermediate-risk or high-risk prostate cancer will experience a
biochemical recurrence after radical prostatectomy. Clinical guidelines for the management …

Radiation with or without antiandrogen therapy in recurrent prostate cancer

WU Shipley, W Seiferheld, HR Lukka… - … England Journal of …, 2017 - Mass Medical Soc
Background Salvage radiation therapy is often necessary in men who have undergone
radical prostatectomy and have evidence of prostate-cancer recurrence signaled by a …

Contemporary update of a multi-institutional predictive nomogram for salvage radiotherapy after radical prostatectomy

RD Tendulkar, S Agrawal, T Gao… - Journal of Clinical …, 2016 - ascopubs.org
Purpose We aimed to update a previously published, multi-institutional nomogram of
outcomes for salvage radiotherapy (SRT) following radical prostatectomy (RP) for prostate …

Improved metastasis-free and survival outcomes with early salvage radiotherapy in men with detectable prostate-specific antigen after prostatectomy for prostate …

BJ Stish, TM Pisansky, WS Harmsen… - Journal of Clinical …, 2016 - ascopubs.org
Purpose To describe outcomes of salvage radiotherapy (SRT) for men with detectable
prostate-specific antigen (PSA) after radical prostatectomy for prostate cancer and identify …

[HTML][HTML] Genomic prostate cancer classifier predicts biochemical failure and metastases in patients after postoperative radiation therapy

RB Den, FY Feng, TN Showalter, MV Mishra… - International Journal of …, 2014 - Elsevier
Purpose To test the hypothesis that a genomic classifier (GC) would predict biochemical
failure (BF) and distant metastasis (DM) in men receiving radiation therapy (RT) after radical …

Association of presalvage radiotherapy PSA levels after prostatectomy with outcomes of long-term antiandrogen therapy in men with prostate cancer

RT Dess, Y Sun, WC Jackson, NK Jairath… - JAMA …, 2020 - jamanetwork.com
Importance In men with recurrent prostate cancer, addition of long-term antiandrogen
therapy to salvage radiotherapy (SRT) was associated with overall survival (OS) in the …

Impact of 68Ga-PSMA PET/CT on salvage radiotherapy planning in patients with prostate cancer and persisting PSA values or biochemical relapse after …

C Bluemel, F Linke, K Herrmann, I Simunovic, M Eiber… - EJNMMI research, 2016 - Springer
Background Salvage radiotherapy (SRT) is clinically established in prostate cancer (PC)
patients with PSA persistence or biochemical relapse (BCR) after prior radical surgery …

Psa-net: Deep learning–based physician style–aware segmentation network for postoperative prostate cancer clinical target volumes

A Balagopal, H Morgan, M Dohopolski… - Artificial Intelligence in …, 2021 - Elsevier
Purpose Automatic segmentation of medical images with deep learning (DL) algorithms has
proven highly successful in recent times. With most of these automation networks, inter …

A deep learning-based framework for segmenting invisible clinical target volumes with estimated uncertainties for post-operative prostate cancer radiotherapy

A Balagopal, D Nguyen, H Morgan, Y Weng… - Medical image …, 2021 - Elsevier
In post-operative radiotherapy for prostate cancer, precisely contouring the clinical target
volume (CTV) to be irradiated is challenging, because the cancerous prostate gland has …