Roadmap: proton therapy physics and biology

H Paganetti, C Beltran, S Both, L Dong… - Physics in Medicine …, 2021 - iopscience.iop.org
The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Adaptive proton therapy

H Paganetti, P Botas, GC Sharp… - Physics in Medicine & …, 2021 - iopscience.iop.org
Radiation therapy treatments are typically planned based on a single image set, assuming
that the patient's anatomy and its position relative to the delivery system remains constant …

The TOPAS tool for particle simulation, a Monte Carlo simulation tool for physics, biology and clinical research

B Faddegon, J Ramos-Méndez, J Schuemann… - Physica Medica, 2020 - Elsevier
Purpose This paper covers recent developments and applications of the TOPAS TOol for
PArticle Simulation and presents the approaches used to disseminate TOPAS. Materials and …

MR-guided proton therapy: a review and a preview

A Hoffmann, B Oborn, M Moteabbed, S Yan… - Radiation …, 2020 - Springer
Background The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is
expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The …

[LIVRE][B] Monte Carlo techniques in radiation therapy

J Seco, F Verhaegen - 2013 - api.taylorfrancis.com
Monte Carlo simulation techniques made a slow entry in the field of radiotherapy in the late
1970s. Since then they have gained enormous popularity, judging by the number of papers …

A full-scale clinical prototype for proton range verification using prompt gamma-ray spectroscopy

F Hueso-González, M Rabe, TA Ruggieri… - Physics in Medicine …, 2018 - iopscience.iop.org
We present a full-scale clinical prototype system for in vivo range verification of proton pencil-
beams using the prompt gamma-ray spectroscopy method. The detection system consists of …

Anatomic changes in head and neck intensity-modulated proton therapy: Comparison between robust optimization and online adaptation

A Lalonde, M Bobić, B Winey, J Verburg… - Radiotherapy and …, 2021 - Elsevier
Background/purpose Setup variations and anatomical changes can severely affect the
quality of head and neck intensity-modulated proton therapy (IMPT) treatments. The impact …

Fred: a GPU-accelerated fast-Monte Carlo code for rapid treatment plan recalculation in ion beam therapy

A Schiavi, M Senzacqua, S Pioli… - Physics in Medicine …, 2017 - iopscience.iop.org
Ion beam therapy is a rapidly growing technique for tumor radiation therapy. Ions allow for a
high dose deposition in the tumor region, while sparing the surrounding healthy tissue. For …

Comparison of weekly and daily online adaptation for head and neck intensity-modulated proton therapy

M Bobić, A Lalonde, GC Sharp… - Physics in Medicine …, 2021 - iopscience.iop.org
The high conformality of intensity-modulated proton therapy (IMPT) dose distributions
causes treatment plans to be sensitive to geometrical changes during the course of a …

Online adaption approaches for intensity modulated proton therapy for head and neck patients based on cone beam CTs and Monte Carlo simulations

P Botas, J Kim, B Winey… - Physics in Medicine & …, 2018 - iopscience.iop.org
Online adaption approaches for intensity modulated proton therapy for head and neck patients
based on cone beam CTs and Monte Carlo simulations - IOPscience Skip to content IOP …