Abstract Ribosome profiling (Ribo-Seq) has proven transformative for our understanding of
the human genome and proteome by illuminating thousands of noncanonical sites of …

Proteins with up to 100 amino acids have been largely overlooked due to the challenges
associated with predicting and identifying them using traditional methods. Recent advances …

The mesophilic methanogenic archaeal model organism Methanosarcina mazei strain Gö1
is crucial for climate and environmental research due to its ability to produce methane. Here …

The ever-growing repertoire of genomic techniques continues to expand our understanding
of the true diversity and richness of prokaryotic genomes. Riboproteogenomics laid the …

The ability to respond to acidic environments is crucial for neutralophilic bacteria.
Escherichia coli has a well-characterized regulatory network that triggers a multitude of …

The soil-dwelling plant symbiont Sinorhizobium meliloti is a major model organism of
Alphaproteobacteria. Despite numerous detailed OMICS studies, information about small …

In contrast to extensively studied prokaryotic 'small'transcriptomes (encompassing all small
noncoding RNAs), small proteomes (here defined as including proteins≤ 70 aa) are only …

Genomic studies of bacteria have long pointed toward widespread prevalence of small open
reading frames (sORFs) encoding for short proteins,< 100 amino acids in length. Despite the …

Microproteins encoded by small open reading frames comprise the" dark matter" of
proteomes. Although microproteins have been detected in diverse organisms from all three …

Small proteins comprising less than 100 amino acids have been often ignored in bacterial
genome annotations. About 10 years ago, focused efforts started to investigate whole …