Human platelet lysate: replacing fetal bovine serum as a gold standard for human cell propagation?
The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …
The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease …
J Galipeau - Cytotherapy, 2013 - Elsevier
The use of cryopreserved unmatched allogeneic mesenchymal stromal cells (MSCs) for
treatment of steroid-resistant graft-versus-host disease has become medical practice in …
treatment of steroid-resistant graft-versus-host disease has become medical practice in …
Fetal bovine serum (FBS): past–present–future
The supplementation of culture medium with fetal bovine serum (FBS, also referred to as
“fetal calf serum”) is still common practice in cell culture applications. Due to a number of …
“fetal calf serum”) is still common practice in cell culture applications. Due to a number of …
A comparative analysis of multipotent mesenchymal stromal cells derived from different sources, with a focus on neuroregenerative potential
Y Petrenko, I Vackova, K Kekulova, M Chudickova… - Scientific reports, 2020 - nature.com
Multipotent mesenchymal stromal cells (MSCs) can be considered an accessible therapeutic
tool for regenerative medicine. Here, we compared the growth kinetics, immunophenotypic …
tool for regenerative medicine. Here, we compared the growth kinetics, immunophenotypic …
Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells
G Siegel, T Kluba, U Hermanutz-Klein, K Bieback… - BMC medicine, 2013 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) are attractive for cell-based
therapies ranging from regenerative medicine and tissue engineering to immunomodulation …
therapies ranging from regenerative medicine and tissue engineering to immunomodulation …
Expansion and characterization of bone marrow derived human mesenchymal stromal cells in serum-free conditions
Bone marrow-derived mesenchymal stromal cells (BM-MSCs) are gaining increasing
importance in the field of regenerative medicine. Although therapeutic value of MSCs is now …
importance in the field of regenerative medicine. Although therapeutic value of MSCs is now …
Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study
G Zheng, L Huang, H Tong, Q Shu, Y Hu, M Ge… - Respiratory …, 2014 - Springer
Background Recent studies have demonstrated that mesenchymal stem cells (MSCs)
modulate the immune response and reduce lung injury in animal models. Currently, no …
modulate the immune response and reduce lung injury in animal models. Currently, no …
Human platelet lysate to substitute fetal bovine serum in hMSC expansion for translational applications: a systematic review
Background Foetal bovine serum (FBS), is the most commonly used culture medium additive
for in vitro cultures, despite its undefined composition, its potential immunogenicity and …
for in vitro cultures, despite its undefined composition, its potential immunogenicity and …
Evaluation of human platelet lysate versus fetal bovine serum for culture of mesenchymal stromal cells
Culture media for therapeutic cell preparations—such as mesenchymal stromal cells (MSCs)—
usually comprise serum additives. Traditionally, fetal bovine serum is supplemented in basic …
usually comprise serum additives. Traditionally, fetal bovine serum is supplemented in basic …
Injectable and tunable hyaluronic acid hydrogels releasing chemotactic and angiogenic growth factors for endodontic regeneration
Bioengineered soft tissues on any meaningful scale or complexity must incorporate aspects
of the functional tissue, namely a vasculature, providing cells oxygen and nutrients critical for …
of the functional tissue, namely a vasculature, providing cells oxygen and nutrients critical for …