A consequence of climate change is the increased frequency and severity of extreme heat
waves. This is occurring now as most of the warmest summers and most intense heat waves …

Environmental signals act primarily on physiological systems, which then influence higher‐
level functions such as movement patterns and population dynamics. Increases in average …

The advent of endothermy, which is achieved through the continuous homeostatic regulation
of body temperature and metabolism,, is a defining feature of mammalian and avian …

Transient receptor potential (TRP) channels are polymodal molecular sensors involved in
numerous physiological processes and implicated in a variety of human diseases. Several …

Caenorhabditis elegans lives in a complex habitat in which they routinely experience large
fluctuations in temperature, and encounter physical obstacles that vary in size and …

Microglia maintain central nervous system homeostasis by monitoring changes in their
environment (resting state) and by taking protective actions to equilibrate such changes …

Mammals maintain a constant warm body temperature, facilitating a wide variety of
metabolic reactions. Mammals that hibernate have the ability to slow their metabolism, which …

Transient receptor potential ankyrin 1 (TRPA1) is a polymodal nonselective cation channel
sensitive to different physical and chemical stimuli. TRPA1 is associated with many …

To cope with temperature fluctuations, molecular thermosensors in animals play a pivotal
role in accurately sensing ambient temperature. Transient receptor potential melastatin 8 …

Highlights•Innocuous thermal information is a key component of haptic exploration.•Thermal
perception is immediate and robust from mouse to man.•Mouse thermosensory system is …