Vitiligo is a multifactorial polygenic disorder with a complex pathogenesis, linked with both
genetic and non‐genetic factors. The precise modus operandi for vitiligo pathogenesis has …

Human epidermal melanocytes play a central role in sensing the environment and
protecting the skin from the drastic effects of solar ultraviolet radiation and other …

Background Vitiligo is a skin disorder characterized by loss of melanocytes from the
epidermis. A recent study reported that CXCL10 is critical for the progression and …

The aim of present study was to evaluate CD4+/CD8+ ratio and CD4+ CD25hiFoxP3+ Tregs
in GV patients with reference to their effect on disease onset and progression. Flow …

Background Vitiligo is an autoimmune disease associated with alteration in levels of various
cytokines. However, there are very few studies in this regard. Objectives To assess the …

Tumour necrosis factor (TNF)‐α, a proinflammatory cytokine central to many autoimmune
diseases, has been implicated in the depigmentation process in vitiligo. We review its role in …

Single nucleotide polymorphisms (SNP) in various genes have been described to be
associated with susceptibility to autoimmune disease. In this study, myalgic …

Vitiligo is an acquired depigmenting disorder which affects both skin and mucous
membranes and autoimmunity has been strongly suggested to play a role in loss of …

Vitiligo is an acquired depigmentation disorder characterized by the loss of functional
melanocytes from the epidermis. Two major theories of vitiligo pathogenesis include …

Interferon-gamma (IFN-γ) is a paracrine inhibitor of melanocytes and genetic variability due
to intron 1 polymorphisms in IFNG has been reported to be associated with increased risk for …