Alginate is a natural polysaccharide present in various marine brown seaweeds. Alginate
oligosaccharide (AOS) is a degradation product of alginate, which has received increasing …

The innate immune response in the central nervous system (CNS) is implicated as both
beneficial and detrimental to health. Integral to this process are microglia, the resident …

Polyguluronic acid (PG), a polysaccharide from alginate, possesses excellent bioactivities.
We prepared high-purity PG with 10.41 kDa molecular weight (Mw) and a 59 average …

Biocompatible and biodegradable biomaterials are used extensively in regenerative
medicine and serve as a tool for tissue replacement, as a platform for regeneration of injured …

Background Vulvovaginal candidiasis (VVC) is a common infectious disease of the lower
genital tract. Nystatin, a polyene fungicidal antibiotic, is used as a topical antifungal agent for …

Prostate cancer is malignant cancer leading to high mortality in the male population. The
existence of suppressive cells referred to as tumor-associated macrophages (TAM) is a …

In vitro experiments demonstrated that stimulation of Toll‐like receptor 9 (TLR‐9) by
synthetic TLR‐9 ligands induces the invasion of TLR‐9‐expressing prostate cancer cells …

Given multiple treatment strategies for prostate cancer, its mortality rate is still high;
therefore, novel treatment strategies seem necessary. G2013 or α‐L‐guluronic acid is a new …

Background: The non-steroidal anti-inflammatory drugs (NSAIDs) play crucial role in the
controlling of inflammatory diseases. Due to the vast side effects of NSAIDs, its use is limited …

Aim: The importance of chronic inflammation during the progression of prostate cancer
(PCa) is well-known. M2000 (β-d-mannuronic acid) is a novel anti-inflammatory drug …