Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

Abstract Calcium (Ca2+) signalling is of paramount importance to immunity. Regulated
increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex …

Ion channels play a central role in the regulation of nearly every cellular process. Dating
back to the classic 1952 Hodgkin–Huxley model of the generation of the action potential, ion …

Vascular smooth muscle (VSM) plays an important role in the regulation of vascular function.
Identifying the mechanisms of VSM contraction has been a major research goal in order to …

Ginger (Zingiber officinale Roscoe) is a common and widely used spice. It is rich in various
chemical constituents, including phenolic compounds, terpenes, polysaccharides, lipids …

Substantial follicle remodelling during the regression phase of the hair growth cycle is
coordinated by the contraction of the dermal sheath smooth muscle, but how dermal-sheath …

Ion channels that influence membrane potential and intracellular calcium concentration
control vascular smooth muscle excitability. Voltage-gated calcium channels (VGCC) …

Testosterone (T) is the predominant endogenous androgen in the bloodstream. At the
vascular level, T presents genomic and non-genomic effects, and both effects may overlap …

Diabetes affects millions of people worldwide. This devastating disease dramatically
increases the risk of develo** cardiovascular disorders. A hallmark metabolic abnormality …

Vascular smooth muscle cells (VSMCs) are the predominant cell type in the arterial wall.
These cells play a critical role in maintaining vascular homeostasis including …