The role of inflammation in venous thromboembolism

BR Branchford, SL Carpenter - Frontiers in pediatrics, 2018‏ - frontiersin.org
Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT), and pulmonary
embolism (PE), is becoming increasingly recognized as a cause of morbidity and mortality in …

Innate immune receptors in platelets and platelet-leukocyte interactions

PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020‏ - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Role of platelet mitochondria: life in a nucleus-free zone

H Melchinger, K Jain, T Tyagi, J Hwa - Frontiers in cardiovascular …, 2019‏ - frontiersin.org
Platelets are abundant, small, anucleate circulating cells, serving many emerging
pathophysiological roles beyond hemostasis; including active critical roles in thrombosis …

Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients

TAM Claushuis, LA van Vught… - Blood, The Journal …, 2016‏ - ashpublications.org
Preclinical studies have suggested that platelets influence the host response during sepsis.
We sought to assess the association of admission thrombocytopenia with the presentation …

Flavonoids and platelet aggregation: A brief review

C Faggio, A Sureda, S Morabito… - European journal of …, 2017‏ - Elsevier
Platelets are small anucleated fragments derived from a megakaryocyte precursor. Platelets
play a key role in many physiological functions especially in hemostasis and wound healing …

Platelets in immune response to virus and immunopathology of viral infections

ED Hottz, FA Bozza, PT Bozza - Frontiers in medicine, 2018‏ - frontiersin.org
Platelets are essential effector cells in hemostasis. Aside from their role in coagulation,
platelets are now recognized as major inflammatory cells with key roles in the innate and …

Platelet membrane camouflaged nanoparticles: biomimetic architecture for targeted therapy

SS Kunde, S Wairkar - International Journal of Pharmaceutics, 2021‏ - Elsevier
Cell membrane coating strategy is one of the promising techniques for biomimetic
functionalization of nanoparticle. The biomimetic nanoparticles camouflage themselves …

Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation

ED Hottz, JF Lopes, C Freitas… - Blood, The Journal …, 2013‏ - ashpublications.org
Dengue is the most frequent hemorrhagic viral disease and re-emergent infection in the
world. Although thrombocytopenia is characteristically observed in mild and severe forms of …

The role of platelets in sepsis

SF de Stoppelaar, C van't Veer… - Thrombosis and …, 2014‏ - thieme-connect.com
Platelets are small circulating anucleate cells that are of crucial importance in haemostasis.
Over the last decade, it has become increasingly clear that platelets play an important role in …

[HTML][HTML] Platelets and multi-organ failure in sepsis

E Greco, E Lupia, O Bosco, B Vizio… - International journal of …, 2017‏ - mdpi.com
Platelets have received increasing attention for their role in the pathophysiology of infectious
disease, inflammation, and immunity. In sepsis, a low platelet count is a well-known …