The current state of peptide drug discovery: back to the future?

A Henninot, JC Collins, JM Nuss - Journal of medicinal chemistry, 2018 - ACS Publications
Over the past decade, peptide drug discovery has experienced a revival of interest and
scientific momentum, as the pharmaceutical industry has come to appreciate the role that …

Peptidomimetic toolbox for drug discovery

E Lenci, A Trabocchi - Chemical Society Reviews, 2020 - pubs.rsc.org
The art of transforming peptides into drug leads is still a dynamic and fertile field in medicinal
chemistry and drug discovery. Peptidomimetics can respond to peptide limitations by …

Addressing MRSA infection and antibacterial resistance with peptoid polymers

J ** macrocyclic peptides that can reach intracellular targets is a significant
challenge. This review discusses the most recent strategies used to develop cell permeable …

Engineering precise sequence-defined polymers for advanced functions

Q Shi, Z Deng, M Hou, X Hu, S Liu - Progress in Polymer Science, 2023 - Elsevier
Unlike natural macromolecules (eg, nucleic acids and proteins) possessing precisely
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …