Alopecia areata: an update on etiopathogenesis, diagnosis, and management

C Zhou, X Li, C Wang, J Zhang - Clinical Reviews in Allergy & …, 2021 - Springer
Alopecia areata (AA) is a common chronic tissue-specific autoimmune disease, resulting in
hair loss, that affects up to 2% of the general population. The exact pathobiology of AA has …

An overview of JAK/STAT pathways and JAK inhibition in alopecia areata

M Lensing, A Jabbari - Frontiers in immunology, 2022 - frontiersin.org
Alopecia Areata (AA) is a common autoimmune disease characterized by non-scarring hair
loss ranging from patches on the scalp to complete hair loss involving the entire body …

Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata: a randomised, double-blind, multicentre, phase 2b–3 trial

B King, X Zhang, WG Harcha, JC Szepietowski… - The Lancet, 2023 - thelancet.com
Background Alopecia areata is characterised by non-scarring loss of scalp, face, or body
hair. We investigated the efficacy and safety of ritlecitinib, an oral, selective dual JAK3/TEC …

Baricitinib for the treatment of alopecia areata

E Freitas, E Guttman-Yassky, T Torres - Drugs, 2023 - Springer
Alopecia areata (AA) is a relapsing, chronic, immune-mediated disease characterized by
nonscarring, inflammatory hair loss that can affect any hair-bearing site. AA clinical …

Alopecia areata–Current understanding and management

DA Lintzeri, A Constantinou, K Hillmann… - JDDG: Journal der …, 2022 - Wiley Online Library
Alopecia areata (AA) is a chronic, immune‐mediated disease characterized by acute or
chronic non‐scarring hair loss, with a heterogeneity in clinical manifestations ranging from …

Deciphering the molecular mechanisms of stem cell dynamics in hair follicle regeneration

JH Lee, S Choi - Experimental & Molecular Medicine, 2024 - nature.com
Hair follicles, which are connected to sebaceous glands in the skin, undergo cyclic periods
of regeneration, degeneration, and rest throughout adult life in mammals. The crucial …

Alopecia areata: a review of the role of oxidative stress, possible biomarkers, and potential novel therapeutic approaches

L Peterle, S Sanfilippo, F Borgia, N Cicero, S Gangemi - Antioxidants, 2023 - mdpi.com
Alopecia areata (AA) is a dermatological condition characterized by non-scarring hair loss.
Exact etiopathogenesis of AA is still unknown although it is known that several factors …

European recommendations for management of immune checkpoint inhibitors‐derived dermatologic adverse events. The EADV task force 'Dermatology for cancer …

Z Apalla, V Nikolaou, D Fattore… - Journal of the …, 2022 - Wiley Online Library
The introduction of immune checkpoint inhibitors (ICIs) opened a new era in oncologic
therapy. The favourable profile of ICIs in terms of efficacy and safety can be overshadowed …

Microneedle‐Mediated Delivery of Immunomodulators Restores Immune Privilege in Hair Follicles and Reverses Immune‐Mediated Alopecia

N Younis, N Puigmal, AE Kurdi, A Badaoui… - Advanced …, 2024 - Wiley Online Library
Disorders in the regulatory arm of the adaptive immune system result in autoimmune‐
mediated diseases. While systemic immunosuppression is the prevailing approach to …

Alopecia areata: current treatments and new directions

D Dahabreh, S Jung, Y Renert-Yuval, J Bar… - American Journal of …, 2023 - Springer
Alopecia areata is an autoimmune hair loss disease that is non-scarring and is
characterized by chronic inflammation at the hair follicle level. Clinically, patients' …