2020 Seoul consensus on the diagnosis and management of gastroesophageal reflux disease

HK Jung, CH Tae, KH Song, SJ Kang… - Journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Gastroesophageal reflux disease (GERD) is a condition in which gastric contents regurgitate
into the esophagus or beyond, resulting in either troublesome symptoms or complications …

The appropriate use of proton pump inhibitors (PPIs): need for a reappraisal

V Savarino, P Dulbecco, N de Bortoli… - European journal of …, 2017 - Elsevier
The advent of powerful acid-suppressive drugs, such as proton pump inhibitors (PPIs), has
revolutionized the management of acid-related diseases and has minimized the role of …

Proton pump inhibitor-induced gut dysbiosis and immunomodulation: current knowledge and potential restoration by probiotics

A Kiecka, M Szczepanik - Pharmacological reports, 2023 - Springer
Proton pump inhibitors (PPIs) are the most commonly prescribed drugs for the treatment of
non-erosive reflux disease (NERD), ulcers associated with non-steroidal anti-inflammatory …

Systematic review: the effects of long‐term proton pump inhibitor use on serum gastrin levels and gastric histology

L Lundell, M Vieth, F Gibson, P Nagy… - Alimentary …, 2015 - Wiley Online Library
Background Proton pump inhibitors (PPI s) have a well‐established safety profile. However,
concerns have been raised about a potential relationship between PPI‐induced …

Proton pump inhibitors: use and misuse in the clinical setting

V Savarino, E Marabotto, P Zentilin… - Expert review of …, 2018 - Taylor & Francis
Introduction: The introduction of proton pump inhibitors (PPIs) into clinical practice has
greatly improved our therapeutic approach to acid-related diseases for their efficacy and …

Use of acid-suppressive drugs and risk of pneumonia: a systematic review and meta-analysis

CS Eom, CY Jeon, JW Lim, EG Cho, SM Park, KS Lee - Cmaj, 2011 - cmaj.ca
Background Observational studies and randomized controlled trials have yielded
inconsistent findings about the association between the use of acid-suppressive drugs and …

EAES recommendations for the management of gastroesophageal reflux disease

KH Fuchs, B Babic, W Breithaupt, B Dallemagne… - Surgical …, 2014 - Springer
Background Gastroesophageal reflux disease (GERD) is one of the most frequent benign
disorders of the upper gastrointestinal tract. Management of GERD has always been …

NERD: an umbrella term including heterogeneous subpopulations

E Savarino, P Zentilin, V Savarino - Nature reviews Gastroenterology & …, 2013 - nature.com
Nonerosive reflux disease (NERD) represents the more common phenotypic presentation of
GERD and comprises patients who have typical symptoms without any mucosal breaks at …