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Frontotemporal lobar degeneration
Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset
dementia and presents with early social–emotional–behavioural and/or language changes …
dementia and presents with early social–emotional–behavioural and/or language changes …
Progranulin as a therapeutic target in neurodegenerative diseases
Progranulin (PGRN, encoded by the GRN gene) plays a key role in the development,
survival, function, and maintenance of neurons and microglia in the mammalian brain. It …
survival, function, and maintenance of neurons and microglia in the mammalian brain. It …
Frontotemporal dementia, where do we stand? A narrative review
Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
Rapidly progressive dementias—aetiologies, diagnosis and management
Rapidly progressive dementias (RPDs) are a group of heterogeneous disorders that include
immune-mediated, infectious and metabolic encephalopathies, as well as prion diseases …
immune-mediated, infectious and metabolic encephalopathies, as well as prion diseases …
[HTML][HTML] Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are fatal
neurodegenerative disorders that are thought to exist on a clinical and pathological …
neurodegenerative disorders that are thought to exist on a clinical and pathological …
C9ORF72: what it is, what it does, and why it matters
J Smeyers, EG Banchi, M Latouche - Frontiers in cellular …, 2021 - frontiersin.org
When the non-coding repeat expansion in the C9ORF72 gene was discovered to be the
most frequent cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis …
most frequent cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis …
Diagnostic contribution and therapeutic perspectives of transcranial magnetic stimulation in dementia
Transcranial magnetic stimulation (TMS) is a powerful tool to probe in vivo brain circuits, as it
allows to assess several cortical properties such as excitability, plasticity and connectivity in …
allows to assess several cortical properties such as excitability, plasticity and connectivity in …
Neuropathology and emerging biomarkers in corticobasal syndrome
Corticobasal syndrome (CBS) is a clinical syndrome characterised by progressive
asymmetric limb rigidity and apraxia with dystonia, myoclonus, cortical sensory loss and …
asymmetric limb rigidity and apraxia with dystonia, myoclonus, cortical sensory loss and …
Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases
Significant progress has been made in understanding the pre-symptomatic phase of
amyotrophic lateral sclerosis. While much is still unknown, advances in other …
amyotrophic lateral sclerosis. While much is still unknown, advances in other …
Genetics of Parkinson's disease
Less than a quarter century after the discovery of SNCA as the first attributable gene in
Parkinson's disease (PD), our knowledge of the genetic architecture underlying this disease …
Parkinson's disease (PD), our knowledge of the genetic architecture underlying this disease …