Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

A single dose of psilocybin, a psychedelic that acutely causes distortions of space–time
perception and ego dissolution, produces rapid and persistent therapeutic effects in human …

Psychedelics have attracted medical interest, but their effects on human brain function are
incompletely understood. In a comprehensive, within-subjects, placebo-controlled design …

Structure–function relationships are a fundamental principle of many naturally occurring
systems. However, network neuroscience research suggests that there is an imperfect link …

This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …

Psychedelics are a unique class of drug that commonly produce vivid hallucinations as well
as profound psychological and mystical experiences. A grou** of interconnected brain …

This theoretical article revives a classical bridging construct, canalization, to describe a new
model of a general factor of psychopathology. To achieve this, we have distinguished …

Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …