Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets

C Gao, J Jiang, Y Tan, S Chen - Signal transduction and targeted …, 2023 - nature.com
Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Are dementia with Lewy bodies and Parkinson's disease dementia the same disease?

KA Jellinger, AD Korczyn - Advances in Surgical and Medical …, 2023 - taylorfrancis.com
The clinical features of dementia with Lewy bodies (DLB) and Parkinson's disease dementia
(PDD) are similar and include dementia, cognitive fluctuations, and (visual) hallucinations in …

Artificial intelligence in neurodegenerative diseases: A review of available tools with a focus on machine learning techniques

AM Tăuţan, B Ionescu, E Santarnecchi - Artificial intelligence in medicine, 2021 - Elsevier
Neurodegenerative diseases have shown an increasing incidence in the older population in
recent years. A significant amount of research has been conducted to characterize these …

Dementia with Lewy bodies and Parkinson's disease-dementia: current concepts and controversies

KA Jellinger - Journal of neural transmission, 2018 - Springer
Dementia with Lewy bodies (DLB) and Parkinson's disease-dementia (PDD), although
sharing many clinical, neurochemical and morphological features, according to DSM-5, are …

Aging, lifestyle and dementia

D Wahl, SM Solon-Biet, VC Cogger, L Fontana… - Neurobiology of …, 2019 - Elsevier
Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …

Current and future prevalence estimates of mild cognitive impairment, dementia, and its subtypes in a population-based sample of people 70 years and older in …

L Gjøra, BH Strand, S Bergh, T Borza… - Journal of …, 2021 - content.iospress.com
Current and Future Prevalence Estimates of Mild Cognitive Impairment, Dementia, and Its
Subtypes in a Population-Based Sample of People 70 Years and Older in Norway: The HUNT …

Epidemiology of aging and associated cognitive disorders: Prevalence and incidence of Alzheimer's disease and other dementias

OL Lopez, LH Kuller - Handbook of clinical neurology, 2019 - Elsevier
The study of the incidence and prevalence of dementia is important to understand the
distribution of dementing illness among age and sex groups, and for the detection of …

Cognitive impairment in older adults: epidemiology, diagnosis, and treatment

NP Palmer, BT Ortega, P Joshi - Psychiatric Clinics, 2022 - psych.theclinics.com
With an increasingly aging population, health care providers will treat a higher number of
patients with cognitive impairment. Identifying cognitive impairment and intervening early …

Autonomic dysfunction in α-synucleinopathies

JJ Mendoza-Velásquez, JF Flores-Vázquez… - Frontiers in …, 2019 - frontiersin.org
The α-synucleinopathies are a group of neurodegenerative diseases characterized by
abnormal accumulation of insoluble α-synuclein in neurons and glial cells, comprising …

Epidemiology of neurological diseases in older adults

J Dumurgier, C Tzourio - Revue neurologique, 2020 - Elsevier
Neurological diseases refer to the diseases that target the nervous system (brain, spine or
nerves). They are the second leading cause of death, and the first cause of severe long-term …