The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in
the past decade. In November 2018, the International Society for Extracellular Vesicles …

We present here miRTrace, the first algorithm to trace microRNA sequencing data back to
their taxonomic origins. This is a challenge with profound implications for forensics …

Dried blood spots (DBS) are biological samples commonly collected from newborns and in
geographic areas distanced from laboratory settings for the purposes of disease testing and …

MicroRNAs (miRNAs) hold great promise as blood-borne and circulating biomarkers for
numerous diseases. However, the reliability of such liquid biopsies is particularly impacted …

Colorectal cancer (CRC) is a leading cause of cancer-related deaths globally, necessitating
the development of sensitive and minimally invasive diagnostic approaches. In this study …

The repertoire of small noncoding RNAs (sncRNAs), particularly miRNAs, in animals is
considered to be evolutionarily conserved. Studies on sncRNAs are often largely based on …

BACKGROUND Small RNAs are key players in the regulation of gene expression and
differentiation. However, many different classes of small RNAs (sRNAs) have been …

RNA sequencing data sets rapidly increase in quantity. For microRNAs (miRNAs), frequently
dozens to hundreds of billion reads are generated per study. The quantification of annotated …

The simultaneous discrimination of let-7 microRNAs (miRNAs) would greatly facilitate the
early diagnosis and prognosis monitoring of diseases. In this work, a molecular beacon DNA …

High-throughput sequencing (HTS) of nucleic acids has revolutionized the biological
sciences and ushered in new prospects for molecular medicine. Also referred to as next …