Behçet's disease is a systemic vasculitis frequently associated with intraocular inflammation.
Recent findings identified independent clinical clusters in Behçet's disease, each involving …

The gut microbiome is a complex ecosystem of microorganisms and their genetic entities
colonizing the gastrointestinal tract. When in balanced composition, the gut microbiome is in …

Optogenetics may enable mutation-independent, circuit-specific restoration of neuronal
function in neurological diseases. Retinitis pigmentosa is a neurodegenerative eye disease …

Purpose To establish a process to evaluate and standardize a state-of-the-art nomenclature
for reporting neovascular age-related macular degeneration (AMD) data. Design Consensus …

Therapeutic targets have been defined for axial and peripheral spondyloarthritis (SpA) in
2012, but the evidence for these recommendations was only of indirect nature. These …

Coronavirus disease 2019 (COVID-19) vaccines can cause transient local and systemic post-
vaccination reactions. The aim of this study was to report uveitis and other ocular …

Background Patients with noninfectious uveitis are at risk for long-term complications of
uncontrolled inflammation, as well as for the adverse effects of long-term glucocorticoid …

REVERSE is a randomized, double-masked, sham-controlled, multicenter, phase 3 clinical
trial that evaluated the efficacy of a single intravitreal injection of rAAV2/2-ND4 in subjects …

Nucleic acids are used in many therapeutic modalities, including gene therapy, but their
ability to trigger host immune responses in vivo can lead to decreased safety and efficacy. In …

Objective To develop recommendations for the screening, monitoring, and treatment of
uveitis in children with juvenile idiopathic arthritis (JIA). Methods Pediatric rheumatologists …