Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

M Karimi, A Ghasemi, PS Zangabad… - Chemical Society …, 2016 - pubs.rsc.org
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …

Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling

A Skardal, T Shupe, A Atala - Drug discovery today, 2016 - Elsevier
Highlights•Traditional drug screening model systems are inadequate.•Organoid-on-a-chip
platforms stand to significantly advance drug and toxicology screening.•A wide variety or …

Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies

S Ahadian, R Civitarese, D Bannerman… - Advanced …, 2018 - Wiley Online Library
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …

Microfluidics in nanoparticle drug delivery; From synthesis to pre-clinical screening

J Ahn, J Ko, S Lee, J Yu, YT Kim, NL Jeon - Advanced drug delivery reviews, 2018 - Elsevier
Microfluidic technologies employ nano and microscale fabrication techniques to develop
highly controllable and reproducible fluidic microenvironments. Utilizing microfluidics, lead …

Organ-on-a-chip platforms for studying drug delivery systems

NS Bhise, J Ribas, V Manoharan, YS Zhang… - Journal of Controlled …, 2014 - Elsevier
Novel microfluidic tools allow new ways to manufacture and test drug delivery systems.
Organ-on-a-chip systems—microscale recapitulations of complex organ functions—promise …

Microfluidics‐based 3D cell culture models: Utility in novel drug discovery and delivery research

N Gupta, JR Liu, B Patel, DE Solomon… - Bioengineering & …, 2016 - Wiley Online Library
The implementation of microfluidic devices within life sciences has furthered the possibilities
of both academic and industrial applications such as rapid genome sequencing, predictive …

Adverse effects of amorphous silica nanoparticles: focus on human cardiovascular health

C Guo, Y Liu, Y Li - Journal of Hazardous Materials, 2021 - Elsevier
Amorphous silica nanoparticle (SiNPs) has tremendous potential for a host of applications,
while its mass production, broad application and environmental release inevitably increase …

The flow of anisotropic nanoparticles in solution and in blood

JT Lovegrove, B Kent, S Förster, CJ Garvey… - …, 2023 - Wiley Online Library
The alignment of anisotropic nanoparticles in flow has been used for a range of applications
such as the preparation of strong fibres and the assembly of in‐plane aligned 1D …

Toxicity evaluation of silica nanoparticles for delivery applications

Y Tan, D Yu, J Feng, H You, Y Bai, J He, H Cao… - Drug Delivery and …, 2023 - Springer
Silica nanoparticles (SiNPs) are being explored as nanocarriers for therapeutics delivery,
which can address a number of intrinsic drawbacks of therapeutics. To translate laboratory …

Action of nanoparticles on platelet activation and plasmatic coagulation

E Fröhlich - Current medicinal chemistry, 2016 - ingentaconnect.com
Nanomaterials can get into the blood circulation after injection or by release from implants
but also by permeation of the epithelium after oral, respiratory or dermal exposure. Once in …