Inflammation balance in skeletal muscle damage and repair
H Tu, YL Li - Frontiers in immunology, 2023 - frontiersin.org
Responding to tissue injury, skeletal muscles undergo the tissue destruction and
reconstruction accompanied with inflammation. The immune system recognizes the …
reconstruction accompanied with inflammation. The immune system recognizes the …
[HTML][HTML] Targeting HMGB1: A potential therapeutic strategy for chronic kidney disease
T Liu, Q Li, Q **, L Yang, H Mao, P Qu… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
High-mobility group protein box 1 (HMGB1) is a member of a highly conserved high-mobility
group protein present in all cell types. HMGB1 plays multiple roles both inside and outside …
group protein present in all cell types. HMGB1 plays multiple roles both inside and outside …
Hepatocyte activation and liver injury following cerebral ischemia promote HMGB1-mediated hepcidin upregulation in hepatocytes and regulation of systemic iron …
We previously reported that high mobility group box 1 (HMGB1), a danger-associated
molecular pattern (DAMP), increases intracellular iron levels in the postischemic brain by …
molecular pattern (DAMP), increases intracellular iron levels in the postischemic brain by …
High mobility group box 1 in human cancer
High mobility group box 1 (HMGB1) is an extremely versatile protein that is located
predominantly in the nucleus of quiescent eukaryotic cells, where it is critically involved in …
predominantly in the nucleus of quiescent eukaryotic cells, where it is critically involved in …
Ferroptosis: a new promising target for hepatocellular carcinoma therapy
Q Xu, L Ren, N Ren, Y Yang, J Pan, Y Zheng… - Molecular and Cellular …, 2024 - Springer
Hepatocellular carcinoma (HCC) is the sixed most common malignant tumor in the world.
The study for HCC is mired in the predicament confronted with the difficulty of early …
The study for HCC is mired in the predicament confronted with the difficulty of early …
Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in cerebral …
Myeloperoxidase (MPO) plays critical role in the pathology of cerebral ischemia–reperfusion
(I/R) injury via producing hypochlorous acid (HOCl) and inducing oxidative modification of …
(I/R) injury via producing hypochlorous acid (HOCl) and inducing oxidative modification of …
Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy
Muscular dystrophies (MDs) are a group of genetic diseases characterized by progressive
muscle wasting associated to oxidative stress and persistent inflammation. It is essential to …
muscle wasting associated to oxidative stress and persistent inflammation. It is essential to …
Changing perspectives from oxidative stress to redox signaling—extracellular redox control in translational medicine
Extensive research has changed the understanding of oxidative stress that has been linked
to every major disease. Today we distinguish oxidative eu-and distress, acknowledging that …
to every major disease. Today we distinguish oxidative eu-and distress, acknowledging that …
The chemokine landscape: one system multiple shades
Leukocyte trafficking is mainly governed by chemokines, chemotactic cytokines, which can
be concomitantly produced in tissues during homeostatic conditions or inflammation. After …
be concomitantly produced in tissues during homeostatic conditions or inflammation. After …
Nutraceuticals and exercise against muscle wasting during cancer cachexia
Cancer cachexia (CC) is a debilitating multifactorial syndrome, involving progressive
deterioration and functional impairment of skeletal muscles. It affects about 80% of patients …
deterioration and functional impairment of skeletal muscles. It affects about 80% of patients …