Polyphenols are widely recognized as the effective antioxidants, which are divided into
flavonoids, phenolic acids, stilbenes, lignans, tannins and so on. They could regulate …

Oxidative stress plays a key role in the pathogenesis of various diseases. Antioxidants
protect the cells and tissues from oxidative stress by scavenging free radicals and reactive …

Flavonoids, the most common plant polyphenols are widely distributed in every species and
possess a broad range of pharmacological activities. The genus Astragalus is the largest in …

Fisetin is a flavonol that shares distinct antioxidant properties with a plethora of other plant
polyphenols. Additionally, it exhibits a specific biological activity of considerable interest as …

In this study, a library of new intriguing flavonol derivatives (1–17) was designed and
synthesized through a facile route involving Algar-Flynn-Oyamada reaction in a one-pot …

Hedyotis diffuse Willd.(HD) and Hedyotis corymbosa (L.) Lam.(HC), two closely related
species of the same genus, are both used for health benefits and disease prevention in …

Multiple myeloma (MM) is still an incurable hematologic malignancy. Although new
therapeutic strategies have been developed to target different pathways in malignant cells …

Herein, we report a synthetic method with improved selectivity for 5-substituted flavonols via
the Algar-Flynn-Oyamada reaction (AFO), by using of sodium carbonate/hydrogen peroxide …

Fisetin, luteolin and genistein, natural polyphenolic compounds of pharmaceutical interest,
were combined with nicotinamide and isonicotinamide with an aim to obtain their cocrystals …

Many of nowadays diseases are due to the oxidative stress resulting from imbalance
between formation and neutralization of free radicals. Intake of dietary antioxidants is …