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Ferroptosis as a potential target for cancer therapy
Ferroptosis is a recently discovered essential type of cell death that is mainly characterized
by iron overload and lipid peroxidation. Emerging evidence suggests that ferroptosis is a …
by iron overload and lipid peroxidation. Emerging evidence suggests that ferroptosis is a …
Smart nanomaterials in cancer theranostics: challenges and opportunities
Cancer is ranked as the second leading cause of death globally. Traditional cancer
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …
An AND logic gate for Magnetic‐Resonance‐Imaging‐Guided ferroptosis therapy of tumors
To improve the magnetic resonance imaging (MRI) efficiency and ferroptosis therapy
efficacy of exceedingly small magnetic iron oxide nanoparticles (IO,< 5 nm) for tumors via …
efficacy of exceedingly small magnetic iron oxide nanoparticles (IO,< 5 nm) for tumors via …
[HTML][HTML] Magnetic nanoparticles for ferroptosis cancer therapy with diagnostic imaging
Ferroptosis offers a novel method for overcoming therapeutic resistance of cancers to
conventional cancer treatment regimens. Its effective use as a cancer therapy requires a …
conventional cancer treatment regimens. Its effective use as a cancer therapy requires a …
Ferroptosis nanomedicine: clinical challenges and opportunities for modulating tumor metabolic and immunological landscape
H Yang, X Yao, Y Liu, X Shen, M Li, Z Luo - Acs Nano, 2023 - ACS Publications
Ferroptosis, a type of regulated cell death driven by iron-dependent phospholipid
peroxidation, has captured much attention in the field of nanomedicine since it was coined in …
peroxidation, has captured much attention in the field of nanomedicine since it was coined in …
Reactive oxygen species-upregulating nanomedicines towards enhanced cancer therapy
Reactive oxygen species (ROS) play a crucial role in physiological and pathological
processes, emerging as a therapeutic target in cancer. Owing to the high concentration of …
processes, emerging as a therapeutic target in cancer. Owing to the high concentration of …
[HTML][HTML] Nanoparticle-mediated synergistic anticancer effect of ferroptosis and photodynamic therapy: Novel insights and perspectives
H Wang, C Qiao, Q Guan, M Wei, Z Li - Asian Journal of Pharmaceutical …, 2023 - Elsevier
Current antitumor monotherapy has many limitations, highlighting the need for novel
synergistic anticancer strategies. Ferroptosis is an iron-dependent form of nonapoptotic cell …
synergistic anticancer strategies. Ferroptosis is an iron-dependent form of nonapoptotic cell …
Biodegradable ferric phosphate nanocarriers with tumor‐specific activation and glutathione depletion for tumor self‐enhanced ferroptosis and chemotherapy
Y Li, W Fan, X Gu, S Liu, T He, S Gou… - Advanced Functional …, 2024 - Wiley Online Library
Ferroptosis is a regulatory cell death that is dependent on iron‐mediated lipid peroxidation
and cell membrane damage. The use of iron‐based nanocarriers to activate ferroptosis is of …
and cell membrane damage. The use of iron‐based nanocarriers to activate ferroptosis is of …
Photothermal nanozymatic nanoparticles induce ferroptosis and apoptosis through tumor microenvironment manipulation for cancer therapy
It is highly desirable to design a single modality that can simultaneously trigger apoptosis
and ferroptosis to efficiently eliminate tumor progression. Herein, a nanosystem based on …
and ferroptosis to efficiently eliminate tumor progression. Herein, a nanosystem based on …
Organic dye-based photosensitizers for fluorescence imaging-guided cancer phototheranostics
Precise diagnosis and treatment of tumors is the current hotspot, which has also given rise to
a new subject named “theranostics”. It is an ideal precision treatment strategy if the agent …
a new subject named “theranostics”. It is an ideal precision treatment strategy if the agent …