Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

SW Dickey, GYC Cheung, M Otto - Nature Reviews Drug Discovery, 2017 - nature.com
The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …

The Mechanisms of Disease Caused by Acinetobacter baumannii

FC Morris, C Dexter, X Kostoulias, MI Uddin… - Frontiers in …, 2019 - frontiersin.org
Acinetobacter baumannii is a Gram negative opportunistic pathogen that has demonstrated
a significant insurgence in the prevalence of infections over recent decades. With only a …

Clinical and pathophysiological overview of Acinetobacter infections: a century of challenges

D Wong, TB Nielsen, RA Bonomo… - Clinical microbiology …, 2017 - Am Soc Microbiol
Acinetobacter is a complex genus, and historically, there has been confusion about the
existence of multiple species. The species commonly cause nosocomial infections …

Cross-protection and cross-feeding between Klebsiella pneumoniae and Acinetobacter baumannii promotes their co-existence

L Semenec, AK Cain, CJ Dawson, Q Liu, H Dinh… - Nature …, 2023 - nature.com
Acinetobacter baumannii and Klebsiella pneumoniae are opportunistic pathogens
frequently co-isolated from polymicrobial infections. The infections where these pathogens …

Carbapenemases: Transforming Acinetobacter baumannii into a Yet More Dangerous Menace

MS Ramirez, RA Bonomo, ME Tolmasky - Biomolecules, 2020 - mdpi.com
Acinetobacter baumannii is a common cause of serious nosocomial infections. Although
community-acquired infections are observed, the vast majority occur in people with …

Diversity and Function of Capsular Polysaccharide in Acinetobacter baumannii

JK Singh, FG Adams, MH Brown - Frontiers in microbiology, 2019 - frontiersin.org
The Gram-negative opportunistic bacterium Acinetobacter baumannii is a significant cause
of hospital-borne infections worldwide. Alarmingly, the rapid development of antimicrobial …

Capsule carbohydrate structure determines virulence in Acinetobacter baumannii

Y Talyansky, TB Nielsen, J Yan… - PLoS …, 2021 - journals.plos.org
Acinetobacter baumannii is a highly antibiotic-resistant bacterial pathogen for which novel
therapeutic approaches are needed. Unfortunately, the drivers of virulence in A. baumannii …

Colistin-phage combinations decrease antibiotic resistance in Acinetobacter baumannii via changes in envelope architecture

X Wang, B Loh, F Gordillo Altamirano, Y Yu… - Emerging microbes & …, 2021 - Taylor & Francis
Multidrug-resistant bacterial infections are becoming increasingly common, with only few
last-resort antibiotics such as colistin available for clinical therapy. An alternative therapeutic …

Coming from the wild: multidrug resistant opportunistic pathogens presenting a primary, not human-linked, environmental habitat

F Sanz-García, T Gil-Gil, P Laborda… - International Journal of …, 2021 - mdpi.com
The use and misuse of antibiotics have made antibiotic-resistant bacteria widespread
nowadays, constituting one of the most relevant challenges for human health at present …