Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022 - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Towards a deeper understanding of the vaginal microbiota

M France, M Alizadeh, S Brown, B Ma, J Ravel - Nature microbiology, 2022 - nature.com
The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …

The placenta harbors a unique microbiome

K Aagaard, J Ma, KM Antony, R Ganu… - Science translational …, 2014 - science.org
Humans and their microbiomes have coevolved as a physiologic community composed of
distinct body site niches with metabolic and antigenic diversity. The placental microbiome …

The vaginal microbiome and preterm birth

JM Fettweis, MG Serrano, JP Brooks, DJ Edwards… - Nature medicine, 2019 - nature.com
The incidence of preterm birth exceeds 10% worldwide. There are significant disparities in
the frequency of preterm birth among populations within countries, and women of African …

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

MG Dominguez-Bello, EK Costello… - Proceedings of the …, 2010 - National Acad Sciences
Upon delivery, the neonate is exposed for the first time to a wide array of microbes from a
variety of sources, including maternal bacteria. Although prior studies have suggested that …

Vaginal microbiome of reproductive-age women

J Ravel, P Gajer, Z Abdo… - Proceedings of the …, 2011 - National Acad Sciences
The means by which vaginal microbiomes help prevent urogenital diseases in women and
maintain health are poorly understood. To gain insight into this, the vaginal bacterial …

Geography, ethnicity or subsistence-specific variations in human microbiome composition and diversity

VK Gupta, S Paul, C Dutta - Frontiers in microbiology, 2017 - frontiersin.org
One of the fundamental issues in the microbiome research is characterization of the healthy
human microbiota. Recent studies have elucidated substantial divergences in the …

The Vaginal Microenvironment: The Physiologic Role of Lactobacilli

E Amabebe, DOC Anumba - Frontiers in medicine, 2018 - frontiersin.org
In addition to being a passage for sperm, menstruum, and the baby, the human vagina and
its microbiota can influence conception, pregnancy, the mode and timing of delivery, and the …

[HTML][HTML] Bacterial vaginosis and its association with infertility, endometritis, and pelvic inflammatory disease

J Ravel, I Moreno, C Simón - American journal of obstetrics and …, 2021 - Elsevier
Bacterial vaginosis, pelvic inflammatory disease, and endometritis are infections of the
genital tract that can lead to many adverse health outcomes, including infertility. Bacterial …

Temporal dynamics of the human vaginal microbiota

P Gajer, RM Brotman, G Bai, J Sakamoto… - Science translational …, 2012 - science.org
Elucidating the factors that im**e on the stability of bacterial communities in the vagina
may help in predicting the risk of diseases that affect women's health. Here, we describe the …