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Community-acquired pneumonia: a review
Importance Community-acquired pneumonia (CAP) results in approximately 1.4 million
emergency department visits, 740 000 hospitalizations, and 41 000 deaths in the US …
emergency department visits, 740 000 hospitalizations, and 41 000 deaths in the US …
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance
The ecological and evolutionary mechanisms of antimicrobial resistance (AMR) emergence
within patients and how these vary across bacterial infections are poorly understood …
within patients and how these vary across bacterial infections are poorly understood …
Antimicrobial resistance: addressing a global threat to humanity
Antimicrobial resistance (AMR) has been prioritized by the World Health Organization
(WHO) as one of the top 10 global public health threats facing humanity [1]. The High-Level …
(WHO) as one of the top 10 global public health threats facing humanity [1]. The High-Level …
Individualised, short-course antibiotic treatment versus usual long-course treatment for ventilator-associated pneumonia (REGARD-VAP): a multicentre, individually …
Background Ventilator-associated pneumonia (VAP) is associated with increased mortality,
prolonged hospitalisation, excessive antibiotic use and, consequently, increased …
prolonged hospitalisation, excessive antibiotic use and, consequently, increased …
Shorter versus longer-course of antibiotic therapy for urinary tract infections in pediatric population: an updated meta-analysis
Urinary tract infections (UTI) affect between 3% to 7.5% of the febrile pediatric population
each year, being one of the most common bacterial infections in pediatrics. Nevertheless …
each year, being one of the most common bacterial infections in pediatrics. Nevertheless …
The evidence base for the optimal antibiotic treatment duration of upper and lower respiratory tract infections: an umbrella review
SME Kuijpers, DTP Buis, KA Ziesemer… - The Lancet Infectious …, 2025 - thelancet.com
Background Many trials, reviews, and meta-analyses have been performed on the
comparison of short versus long antibiotic treatment in respiratory tract infections, generally …
comparison of short versus long antibiotic treatment in respiratory tract infections, generally …
Short-term versus usual-term antibiotic treatment for uncomplicated Staphylococcus aureus bacteremia: a systematic review and meta-analysis
S Grillo Perez, C Diaz-Brochero… - Therapeutic …, 2024 - journals.sagepub.com
Introduction: Uncomplicated Staphylococcus aureus bacteremia remains a leading cause of
morbidity and mortality in hospitalized patients. Current guidelines recommend a minimum …
morbidity and mortality in hospitalized patients. Current guidelines recommend a minimum …
Synthesis, biological evaluation, and DFT analysis of s-triazine analogues with medicinal potential integrated with bioactive heterocyclic scaffolds
This paper introduces a series of novel s-triazine analogues (designated as compounds (14–
26) incorporating diverse bioactive heterocyclic scaffolds such as 1-adamantylamine …
26) incorporating diverse bioactive heterocyclic scaffolds such as 1-adamantylamine …
Protecting healthcare and patient pathways from infection and antimicrobial resistance
Protecting healthcare and patient pathways from infection and antimicrobial resistance Page 1
RESEARCH PRIORITIES FOR FUTURE SHOCKS Protecting healthcare and patient pathways …
RESEARCH PRIORITIES FOR FUTURE SHOCKS Protecting healthcare and patient pathways …
Exploring Prior Antibiotic Exposure Characteristics for COVID-19 Hospital Admission Patients: OpenSAFELY
Previous studies have demonstrated the association between antibiotic use and severe
COVID-19 outcomes. This study aimed to explore detailed antibiotic exposure …
COVID-19 outcomes. This study aimed to explore detailed antibiotic exposure …