Triple negative breast cancer treatment options and limitations: future outlook

O Obidiro, G Battogtokh, EO Akala - Pharmaceutics, 2023 - mdpi.com
Triple negative breast cancer (TNBC) has a negative expression of estrogen receptors (ER),
progesterone receptors (PR), and human epidermal growth factor receptors (HER2). The …

Opportunities and challenges for co-delivery nanomedicines based on combination of phytochemicals with chemotherapeutic drugs in cancer treatment

Q Gao, J Feng, W Liu, C Wen, Y Wu, Q Liao… - Advanced drug delivery …, 2022 - Elsevier
The therapeutic limitations such as insufficient efficacy, drug resistance, metastasis, and
undesirable side effects are frequently caused by the long duration monotherapy based on …

Nano-drug co-delivery system of natural active ingredients and chemotherapy drugs for cancer treatment: a review

B Li, H Shao, L Gao, H Li, H Sheng, L Zhu - Drug Delivery, 2022 - Taylor & Francis
Chemotherapy drugs have been used for a long time in the treatment of cancer, but serious
side effects are caused by the inability of the drug to be solely delivered to the tumor when …

Natural and synthetic nanovectors for cancer therapy

A Eftekhari, C Kryschi, D Pamies, S Gulec… - …, 2023 - pmc.ncbi.nlm.nih.gov
Nanomaterials have been extensively studied in cancer therapy as vectors that may improve
drug delivery. Such vectors not only bring numerous advantages such as stability …

Polymeric micelles in cancer therapy: State of the art

B Ghosh, S Biswas - Journal of Controlled Release, 2021 - Elsevier
In recent years, polymeric micelles have been extensively utilized in pre-clinical studies for
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …

[HTML][HTML] Progress in polymeric micelles for drug delivery applications

S Kotta, HM Aldawsari, SM Badr-Eldin, AB Nair, K Yt - Pharmaceutics, 2022 - mdpi.com
Polymeric micelles (PMs) have made significant progress in drug delivery applications. A
robust core–shell structure, kinetic stability and the inherent ability to solubilize hydrophobic …

Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval

D Hwang, JD Ramsey, AV Kabanov - Advanced drug delivery reviews, 2020 - Elsevier
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

AP Singh, A Biswas, A Shukla, P Maiti - Signal transduction and …, 2019 - nature.com
The application of nanomedicines is increasing rapidly with the promise of targeted and
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …

The in vivo fate of polymeric micelles

Y Cai, J Qi, Y Lu, H He, W Wu - Advanced Drug Delivery Reviews, 2022 - Elsevier
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

Smart nanocarriers as an emerging platform for cancer therapy: A review

M Kenchegowda, M Rahamathulla, U Hani, MY Begum… - Molecules, 2021 - mdpi.com
Cancer is a group of disorders characterized by uncontrolled cell growth that affects around
11 million people each year globally. Nanocarrier-based systems are extensively used in …