Virtual patient framework for the testing of mechanical ventilation airway pressure and flow settings protocol

CYS Ang, JWW Lee, YS Chiew, X Wang, CP Tan… - Computer Methods and …, 2022 - Elsevier
Abstract Background and Objective Model-based and personalised decision support
systems are emerging to guide mechanical ventilation (MV) treatment for respiratory failure …

Predicting mechanically ventilated patients future respiratory system elastance–A stochastic modelling approach

CYS Ang, YS Chiew, X Wang, MBM Nor… - Computers in Biology …, 2022 - Elsevier
Background and objective Respiratory mechanics of mechanically ventilated patients evolve
significantly with time, disease state and mechanical ventilation (MV) treatment. Existing …

Data-driven discovery of anomaly-sensitive parameters from uvula wake flows using wavelet analyses and Poincaré maps

X Si, J Wang, H Dong, J ** - Acoustics, 2023 - mdpi.com
This study presents a data-driven approach to identifying anomaly-sensitive parameters
through a multiscale, multifaceted analysis of simulated respiratory flows. The anomalies …

Structural performance and damage prediction using a novel digital cloning technique

M Rabiepour, C Zhou… - Structural Health …, 2023 - journals.sagepub.com
This paper presents a novel, mechanics-based framework to create digital twins for
earthquake-affected pinched structures, like reinforced concrete framed buildings. It uses …

[HTML][HTML] Stochasticity of the respiratory mechanics during mechanical ventilation treatment

CYS Ang, YS Chiew, X Wang, MBM Nor… - Results in Engineering, 2023 - Elsevier
Stochastic models have been used to predict dynamic intra-patient respiratory system
elastance (E rs) in mechanically ventilated (MV) patients. However, existing E rs stochastic …

Low-cost structured light imaging of regional volume changes for use in assessing mechanical ventilation

C Zhou, JG Chase - Computer Methods and Programs in Biomedicine, 2022 - Elsevier
Background Optimal setting of mechanical ventilators is critical for improving outcomes.
Accurate, predictive lung mechanics models are effective in optimizing MV settings, but only …

Automated evaluation of typical patient–ventilator asynchronies based on lung hysteretic responses

Y Chen, K Zhang, C Zhou, JG Chase, Z Hu - BioMedical Engineering …, 2023 - Springer
Background Patient–ventilator asynchrony is common during mechanical ventilation (MV) in
intensive care unit (ICU), leading to worse MV care outcome. Identification of asynchrony is …

Pulmonary response prediction through personalized basis functions in a virtual patient model

T Caljé-van der Klei, Q Sun, JG Chase, C Zhou… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objective Recruitment maneuvers with subsequent positive-end-
expiratory-pressure (PEEP) have proven effective in recruiting lung volume and preventing …

[HTML][HTML] Virtual patient with temporal evolution for mechanical ventilation trial studies: A stochastic model approach

CYS Ang, YS Chiew, X Wang, EH Ooi, MBM Nor… - Computer Methods and …, 2023 - Elsevier
Background and objective Healthcare datasets are plagued by issues of data scarcity and
class imbalance. Clinically validated virtual patient (VP) models can provide accurate in …

[HTML][HTML] Design and evaluation of portable emergency ventilator prototype with novel titration methods

B Ding, F Xu, J Wang, C Pan, J Pang, Y Chen… - … Signal Processing and …, 2023 - Elsevier
Mechanical ventilation is considered to be an effective treatment in cardiopulmonary
resuscitation (CPR). Traditional ventilators are not suitable for prompt out-of-hospital first aid …