In recent years, accumulating evidence has elucidated the role of lysosomes in dynamically
regulating cellular and organismal homeostasis. Lysosomal changes and dysfunction have …

Ferrocene is an important structural core in bioorganometallic chemistry because of its
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …

Sorafenib is the first-line medication for advanced hepatocellular carcinoma (HCC), but it
can only extend limited survival. It is imperative to find a combination strategy to increase …

Cancer is one of the most fatal threatens to human health throughout the world. The major
challenges in the control and eradication of cancers are the continuous emergency of drug …

Therapeutic efficacy against cancer relies heavily on the ability of the therapeutic agents to
reach their final targets. The optimal targets of most cancer therapeutic agents are usually …

Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …

Organelles perform critical biological functions due to their distinct molecular composition
and internal environment. Disorders in organelles or their interacting networks have been …

Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …

Artemisinins are a unique class of antimalarial drugs with significant potential for drug
repurposing for a wide range of diseases including cancer. Cancer is a leading cause of …

The emergence of drug-resistance and the low specificity of anticancer agents are the major
challenges in the treatment of cancer and can result in many side effects, creating an urgent …