Metabolites produced by commensal gut microbes impact host health through their
recognition by the immune system and their influence on numerous metabolic pathways …

The gut microbiota, housing trillions of microorganisms within the gastrointestinal tract, has
emerged as a critical regulator of host health and homeostasis. Through complex metabolic …

Background Non-alcoholic fatty liver disease (NAFLD) represents a severe public health
problem. Dysbiosis of gut microbiome has been identified as one of the key environmental …

Propionate is a short-chain fatty acid that is generated upon microbiome-mediated fiber
fermentation in the intestine. By modulating immune and metabolic pathways, propionate …

Prokaryotes have evolved a multitude of defense systems to protect against phage
predation. Some of these resemble eukaryotic genes involved in antiviral responses. Here …

Plant microbiomes are assembled and modified through a complex milieu of biotic and
abiotic factors. Despite dynamic and fluctuating contributing variables, specific host …

Chronic constipation (CC) is a common gastrointestinal condition associated with intestinal
inflammation, and the condition considerably impairs patients' quality of life. We conducted a …

Bacteria produce an array of diverse, dynamic and often complex lipid structures, some of
which function beyond their typical role in membrane structure. The model organism, E. coli …

The gut microbiota plays a significant role in influencing human immunity, metabolism,
development, and behavior by producing a wide range of metabolites. While there is …

Adenine is frequently utilized as a model medication for chronic renal disease. Adenine can
affect organs other than the kidneys, including the heart and the intestine. The liver is a vital …