Trends in mechanobiology guided tissue engineering and tools to study cell-substrate interactions: a brief review

AK Rajendran, D Sankar, S Amirthalingam… - Biomaterials …, 2023 - Springer
Sensing the mechanical properties of the substrates or the matrix by the cells and the
tissues, the subsequent downstream responses at the cellular, nuclear and epigenetic levels …

Passive myocardial mechanical properties: meaning, measurement, models

R Emig, CM Zgierski-Johnston, V Timmermann… - Biophysical …, 2021 - Springer
Passive mechanical tissue properties are major determinants of myocardial contraction and
relaxation and, thus, shape cardiac function. Tightly regulated, dynamically adapting …

Mechanical properties of cell sheets and spheroids: the link between single cells and complex tissues

YM Efremov, IM Zurina, VS Presniakova… - Biophysical …, 2021 - Springer
Cell aggregates, including sheets and spheroids, represent a simple yet powerful model
system to study both biochemical and biophysical intercellular interactions. However, it is …

Enhancing the osteogenic differentiation of aligned electrospun poly (L-lactic acid) nanofiber scaffolds by incorporation of bioactive calcium silicate nanowires

Z Fu, D Li, K Lin, B Zhao, X Wang - International Journal of Biological …, 2023 - Elsevier
Bone defects cause serious psychological and economic burden to patients. Artificially bone
repairing materials bring hope to the treatment of bone defects. Electrospun technique has …

Thiolene-and polycaprolactone methacrylate-based polymerized high internal phase emulsion (PolyHIPE) scaffolds for tissue engineering

B Aldemir Dikici, A Malayeri, C Sherborne… - …, 2021 - ACS Publications
Highly porous emulsion templated polymers (PolyHIPEs) provide a number of potential
advantages in the fabrication of scaffolds for tissue engineering and regenerative medicine …

Engineered cell culture microenvironments for mechanobiology studies of brain neural cells

L Castillo Ransanz, PFJ Van Altena… - … in bioengineering and …, 2022 - frontiersin.org
The biomechanical properties of the brain microenvironment, which is composed of different
neural cell types, the extracellular matrix, and blood vessels, are critical for normal brain …

Cancer-nano-interaction: From cellular uptake to mechanobiological responses

A Sohrabi Kashani, M Packirisamy - International Journal of Molecular …, 2021 - mdpi.com
With the advancement of nanotechnology, the nano-bio-interaction field has emerged. It is
essential to enhance our understanding of nano-bio-interaction in different aspects to design …

Exploiting matrix stiffness to overcome drug resistance

HB Aydin, A Ozcelikkale, A Acar - ACS Biomaterials Science & …, 2024 - ACS Publications
Drug resistance is arguably one of the biggest challenges facing cancer research today.
Understanding the underlying mechanisms of drug resistance in tumor progression and …

[HTML][HTML] Role of actin-binding proteins in the regulation of cellular mechanics

AV Vakhrusheva, AV Murashko, ES Trifonova… - European Journal of …, 2022 - Elsevier
The viscoelastic parameters of the cell can report on the cell state, cellular processes and
diseases. Cell mechanics strongly rely on the properties of the cytoskeleton, an important …

Modulation of hydrogel stiffness by external stimuli: soft materials for mechanotransduction studies

MS Ting, J Travas-Sejdic, J Malmström - Journal of Materials Chemistry …, 2021 - pubs.rsc.org
Mechanotransduction is an important process in determining cell survival, proliferation,
migration and differentiation. The extracellular matrix (ECM) is the component of natural …