D-ɑ-tocopheryl polyethylene glycol succinate (Vitamin E TPGS or TPGS) has been
approved by FDA as a safe adjuvant and widely used in drug delivery systems. The …

Doxorubicin (DOX)-induced toxicity and resistance are major obstacles in chemotherapeutic
approaches. Despite effective in the treatment of numerous malignancies, some clinicians …

Although the chemotherapeutic drug, doxorubicin, is commonly used to treat various
malignant tumors, its clinical use is restricted because of its toxicity especially cardiotoxicity …

Natural compounds, primarily derived from plants, have been isolated and evaluated as
alternative and complementary treatments for cancer. Curcumin has been proven to be …

Background Quercetin (QCT), a naturally occurring flavonoid has a wide array of
pharmacological properties such as anticancer, antioxidant and anti-inflammatory activities …

Accumulating evidence has shown that Signal Transducer and Activator of Transcription 3
(STAT3) is thought to be a promising target for cancer therapy as STAT3 is frequently …

Colorectal cancer remains to be the most prevalent malignancy in humans and 1.5 million
men and women living in the United States are diagnosed with colorectal cancer, with a …

Nutraceuticals provide many biological benefits besides their basic nutritional value.
However, their biological efficacies are often limited by poor absorption and low …

Development of multidrug resistance against chemotherapeutic drugs is one of the major
obstacles to successful cancer therapy in the clinic. Thus far, amphiphilic polymeric micelles …

Cancer continues to be one in all the leading reasons for death worldwide. The mean
cancer survival through standard therapeutic strategies has not been significantly improved …