Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …

There has been rapid growth in the use of Drosophila and other invertebrate systems to
dissect mechanisms governing metabolism. New assays and approaches to physiology …

Sleep is thought to be restorative to brain energy homeostasis, but it is not clear how this is
achieved. We show here that Drosophila glia exhibit a daily cycle of glial mitochondrial …

During starvation, mammalian brains can adapt their metabolism, switching from glucose to
alternative peripheral fuel sources. In the Drosophila starved brain, memory formation is …

The gut microbiota affects the physiology and metabolism of animals and its alteration can
lead to diseases such as gut dysplasia or metabolic disorders. Several reports have shown …

Sex differences in complex traits are suspected to be in part due to widespread gene-by-sex
interactions (GxSex), but empirical evidence has been elusive. Here, we infer the mixture of …

Infection with pathogenic microbes is a severe threat that hosts manage by activating the
innate immune response. In Drosophila melanogaster, the Toll and Imd signaling pathways …

Protein is essential for all living organisms; however, excessive protein intake can have
adverse effects, such as hyperammonemia. Although mechanisms responding to protein …

Lipid droplets are highly dynamic intracellular organelles that store neutral lipids such as
cholesteryl esters and triacylglycerols. They have recently emerged as key stress response …

The intestine is a central regulator of metabolic homeostasis. Dietary inputs are absorbed
through the gut, which senses their nutritional value and relays hormonal information to …