The serotonin hypothesis of depression is still influential. We aimed to synthesise and
evaluate evidence on whether depression is associated with lowered serotonin …

Digital technologies change the healthcare environment, with several studies suggesting
barriers and facilitators to using digital interventions by healthcare professionals (HPs). We …

Schizophrenia substantially contributes to the burden of mental disorders. Schizophrenia's
burden and epidemiological estimates in some countries have been published, but updated …

Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …

Background There remains uncertainty about the impact of the Coronavirus Disease 2019
(COVID-19) pandemic on mental health. This umbrella review provides a comprehensive …

Aims The aim of this study was to investigate the causal relationship and evidence of an
association between increased adiposity and the risk of incident cardiovascular disease …

Importance Detection, prognosis, and indicated interventions in individuals at clinical high
risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To …

Decades of research have revealed numerous risk factors for mental disorders beyond
genetics, but their consistency and magnitude remain uncertain. We conducted a “meta …

Mobile phone-based interventions have been proposed as a means for reducing the burden
of disease associated with mental illness. While numerous randomized controlled trials and …

Background This study applies an umbrella review approach to summarise the global
evidence on the risk of severe COVID-19 outcomes in patients with pre-existing health …